Evidence map›Paper›PMID 39235454›Full record

ArticleeLife2024

Fani Roumelioti, Christos Tzaferis, Dimitris Konstantopoulos, Dimitra Papadopoulou, Alejandro Prados, Maria Sakkou, Anastasios Liakos, Panagiotis Chouvardas, Theodore Meletakos, Yiannis Pandis and 5 more

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Fani RoumeliotiInstitute for Bioinnovation, Biomedical Sciences Research Centre (BSRC) "Alexander Fleming", Vari, Greece.ORCID https://orcid.org/0000-0003-0112-6601
Christos TzaferisInstitute for Bioinnovation, Biomedical Sciences Research Centre (BSRC) "Alexander Fleming", Vari, Greece.
Dimitris KonstantopoulosInstitute for Bioinnovation, Biomedical Sciences Research Centre (BSRC) "Alexander Fleming", Vari, Greece.
Dimitra PapadopoulouInstitute for Bioinnovation, Biomedical Sciences Research Centre (BSRC) "Alexander Fleming", Vari, Greece.
Alejandro PradosInstitute for Bioinnovation, Biomedical Sciences Research Centre (BSRC) "Alexander Fleming", Vari, Greece.
Maria SakkouInstitute for Bioinnovation, Biomedical Sciences Research Centre (BSRC) "Alexander Fleming", Vari, Greece.
Anastasios LiakosInstitute for Fundamental Biomedical Research, Biomedical Sciences Research Center "Alexander Fleming", Vari, Greece.
Panagiotis ChouvardasInstitute for Bioinnovation, Biomedical Sciences Research Centre (BSRC) "Alexander Fleming", Vari, Greece.
Theodore MeletakosInstitute for Fundamental Biomedical Research, Biomedical Sciences Research Center "Alexander Fleming", Vari, Greece.
Yiannis PandisInstitute for Bioinnovation, Biomedical Sciences Research Centre (BSRC) "Alexander Fleming", Vari, Greece.
Niki KaragianniBiomedcode Hellas SA, Vari, Greece.
Maria C DenisBiomedcode Hellas SA, Vari, Greece.
Maria FousteriInstitute for Fundamental Biomedical Research, Biomedical Sciences Research Center "Alexander Fleming", Vari, Greece.
Maria ArmakaInstitute for Fundamental Biomedical Research, Biomedical Sciences Research Center "Alexander Fleming", Vari, Greece.ORCID https://orcid.org/0000-0003-0985-9076
George KolliasInstitute for Bioinnovation, Biomedical Sciences Research Centre (BSRC) "Alexander Fleming", Vari, Greece.ORCID https://orcid.org/0000-0003-1867-3150

Funding

Hellenic Foundation for Research and Innovation HFRI-FM17C3-3780, SingleOutHORIZON EUROPE European Research Council 10.3030/101055093Innovative Medicines Initiative 115142-2 BTCureOperational Programme "Competitiveness, Entrepreneurship and Innovation", NSRF 2014-2020, ERDF, EU/Greece MIS 5002135 ΙnfrafrontierGROperational Programme "Competitiveness, Entrepreneurship and Innovation", NSRF 2014-2020, ERDF, EU/Greece MIS 5002802 pMedGRRegional Operational Programme "ATTICA" (NSRF 2021-2027), ERDF, Greece/EU MIS 6004752
6 · The paper itself

Abstract

miRNAs constitute fine-tuners of gene expression and are implicated in a variety of diseases spanning from inflammation to cancer. miRNA expression is deregulated in rheumatoid arthritis (RA); however, their specific role in key arthritogenic cells such as the synovial fibroblast (SF) remains elusive. Previous studies have shown that

Indexed as

MicroRNAsAnimalsArthritis, RheumatoidChromatin Assembly and DisassemblyFibroblastsGene Expression RegulationMiceSynovial MembraneMicroRNAsMIRN221 microRNA, mouseMIRN222 microRNA, mousecell proliferationexpansionimmunologyinflammationmiRNAsmouserheumatoid arthritissc-ATAC seqsynovial fibroblasts

Identifiers

PMID39235454
PMCPMC11377061

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.