Evidence mapPaperPMID 39235706Full record

ArticleDiscover oncology2024

Knocking down RAD51AP1 enhances chemosensitivity by inhibiting the self-renewal of CD133 positive ovarian cancer stem-like cells.

Si-Heng Zeng, Zhi-Qiang Yan, Qing Ren, Li-Hui Lin, Zhen Chen

Abstract read
In one paragraph

Article in Discover oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Si-Heng ZengDepartment of Gynecology, Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University, Shanghai, 200170, China.
Zhi-Qiang YanDepartment of Gynecology, Hainan West Central Hospital, Danzhou, 571700, China.
Qing RenDepartment of Gynecology, The Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200120, China.
Li-Hui LinDepartment of Gynecology, Hainan West Central Hospital, Danzhou, 571700, China.
Zhen ChenDepartment of Gynecology, Hainan West Central Hospital, Danzhou, 571700, China. 763659186@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study was designed to investigate the function of RAD51AP1 in the self-renewal and chemosensitivity of CD133 positive (CD133

methodsCD133

resultsThe performance of CD133

conclusionThe findings of this study showed that RAD51AP1 was highly expressed in OC tissue and CD133

Indexed as

Cancer drug resistanceOvarian cancerRAD51AP1Tumor proliferation

Identifiers

PMID39235706
PMCPMC11377390

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.