Evidence map›Paper›PMID 39236144›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2024

Aging delays the suppression of lipolysis and fatty acid oxidation in the postprandial period.

Adam D Osmond, Robert G Leija, Jose A Arevalo, Casey C Curl, Justin J Duong, Melvin J Huie, Umesh Masharani, George A Brooks

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Resilience of the mitochondrial reticulum in aging.American journal of physiology. Endocrinology and metabolism · 2025
    Article
  3. The mitochondrial lactate oxidation complex: endpoint for carbohydrate carbon disposal.American journal of physiology. Endocrinology and metabolism · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adam D OsmondExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, California, United States.
Robert G LeijaExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, California, United States.ORCID 0000-0002-7862-293X
Jose A ArevaloExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, California, United States.ORCID 0000-0002-1120-4960
Casey C CurlExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, California, United States.
Justin J DuongExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, California, United States.
Melvin J HuieExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, California, United States.
Umesh MasharaniDivision of Endocrinology, Department of Medicine, University of California, San Francisco, California, United States.
George A BrooksExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, California, United States.ORCID 0000-0002-1389-1629

Funding

HHS | NIH | National Institute on Aging (NIA) R01 AG059715-01NIA NIH HHS R01 AG059715
6 · The paper itself

Abstract

Plasma glycerol and free fatty acid concentrations decrease following oral glucose consumption, but changes in the rate of lipolysis during an oral glucose tolerance test (OGTT) have not been documented in conjunction with changes in fatty acid (FA) oxidation or reesterification rates in healthy individuals. After a 12-h overnight fast, 15 young (21-35 yr; 7 men and 8 women) and 14 older (60-80 yr; 7 men and 7 women) participants had the forearm vein catheterized for primed continuous infusion of [1,1,2,3,3-

Indexed as

AgingFatty AcidsGlycerolLipolysisOxidation-ReductionPostprandial PeriodAdultAgedAged, 80 and overBlood GlucoseFatty Acids, NonesterifiedFemaleGlucose Tolerance TestHumansMaleMiddle AgedBlood GlucoseFatty AcidsFatty Acids, NonesterifiedGlycerolaginglactatemetabolic flexibilityOGTTreesterification

Identifiers

PMID39236144
PMCPMC11563596

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.