ArticleScience (New York, N.Y.)2024
The use of ectopic volar fibroblasts to modify skin identity.
Abstract read
In one paragraph
Article in Science (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Trimodal, uncertainty-guided whole-slide framework for genome-scale spatial expression and image-only virtual perturbation in cancer cohorts.Genome medicine · 2026Article
- Single-cell spatial transcriptomic analysis of human skin anatomy.Nature genetics · 2026Article
- Article
- Advances in Bioprinting to Model Immune-Mediated Skin Diseases.Advanced healthcare materials · 2026Review
- AIstain: Enhancing microglial phagocytosis analysis through deep learning.Cell reports methods · 2025Article
- Transcriptome profiling of human dermal MDPL fibroblasts reveals a characteristic molecular signature providing insights into pathogenic mechanisms.Journal of molecular medicine (Berlin, Germany) · 2025Article
- A single-cell spatial transcriptomic census of human skin anatomy.bioRxiv : the preprint server for biology · 2025Article
- Cell Therapy and the Skin: Great Potential but in Need of Optimization.The Journal of investigative dermatology · 2025Review
- Volar Fibroblasts and their Potential Therapeutic Use.The Journal of investigative dermatology · 2025Article
- Evolution of long scalp hair in humans.The British journal of dermatology · 2025Review
Corrections and comments
- Commented on by
Authors and funding
43 authors.
Sam S LeeDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0003-3760-8960
Evan SwerenDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0001-6664-8174
Erika DareDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0003-2915-8912
Paige DerrDivision of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA.
Kristy DerrDivision of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA.
Chen Chia WangDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0009-0001-9491-7586
Brooke HardestyDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0009-0001-9556-820X
Aiden A WillisDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0002-1812-5085
Junjie ChenDepartment of Mechanical Engineering, Johns Hopkins University, MD 21210, USA.ORCID 0000-0002-3258-0236
Jonathan K VuillierDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0009-0006-9124-233X
Joseph DuDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0009-0003-9812-3366
Julia WoolDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0001-7778-5529
Amanda RuciDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0001-7575-5051
Vicky Y WangDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0002-3171-1927
Chaewon LeeDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0002-0277-8559
Sampada IyengarDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0009-0006-4987-6793
Soichiro AsamiDepartment of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0001-9583-3707
Maria DaskamDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0002-2187-8029
Claudia LeeDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.
Jeremy C LeeDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0009-0001-0832-9906
Darren ChoDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0009-0000-4278-0373
Joshua KimDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.
Eddie Gibson Martinez-PeñaDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0003-4545-7154
So Min LeeDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0009-0001-2347-0473
Xu HeDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.
Michael WakemanDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.
Iralde SiciliaDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.
Dalhart T DobbsDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0009-0001-9732-2852
Amy van EeDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0002-1277-3137
Ang LiDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0002-3421-5726
Yingchao XueDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0002-7830-3146
Kaitlin L WilliamsDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0002-8768-0488
Charles S KirbyDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0001-7756-2114
Dongwon KimDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0001-5740-934X
Sooah KimDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0002-9096-4879
Lillian XuDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0002-1173-8938
Ruizhi WangDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.
Marc FerrerDivision of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA.
Yun ChenDepartment of Mechanical Engineering, Johns Hopkins University, MD 21210, USA.ORCID 0000-0001-6917-7814
Jin U KangDepartment of Electrical and Computer Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0001-5817-1935
Reza KalhorDepartment of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0002-5558-7545
Sewon KangDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0002-7841-9392
Luis A GarzaDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.ORCID 0000-0002-6547-9695
Funding
Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Anna Palmer Durbin · 2012 to 2026
$67.0MMedical Scientist Training ProgramT32GM136577 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ANDREA L COX · 2020 to 2026
$13.4MRetinoic acid synthesis induced by noncoding dsRNA controls RegenerationR01AR074846 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI GARZA, LUIS ANDRES · 2019 to 2023
$2.3MInjection of autologous volar fibroblasts to the stump site to allow pressure adaptation and enhanced prosthetic use in amputeesUH3AR079376 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI Luis Andres Garza · 2023 to 2026
$2.1MMechanism and clinical pilot tst of volar fibroblast to create ectopic volar skinR01AR064297 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI GARZA, LUIS ANDRES · 2013 to 2017
$1.8MInjection of autologous volar fibroblasts to the stump site to allow pressure adaptation and enhanced prosthetic use in amputeesUG3AR079376 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI GARZA, LUIS ANDRES · 2021 to 2021
$532kInhibition of Regeneration Restraining Pathways to Promote HealingR56AR082660 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI GARZA, LUIS ANDRES · 2023 to 2023
$360kMoFlo to MoFlo XDP Upgrade for BSL3 SortingS10OD016315 · OD · JOHNS HOPKINS UNIVERSITY · PI MARGOLICK, JOSEPH B. · 2013 to 2013
$233kNIAID NIH HHS P30 AI094189NIAMS NIH HHS R01 AR064297NIAMS NIH HHS R01 AR074846NIAMS NIH HHS R56 AR082660NIAMS NIH HHS UG3 AR079376NIAMS NIH HHS UH3 AR079376NIGMS NIH HHS T32 GM136577NIH HHS S10 OD016315
Abstract
Skin identity is controlled by intrinsic features of the epidermis and dermis and their interactions. Modifying skin identity has clinical potential, such as the conversion of residual limb and stump (nonvolar) skin of amputees to pressure-responsive palmoplantar (volar) skin to enhance prosthesis use and minimize skin breakdown. Greater keratin 9 (
Indexed as
Biomedical EnhancementBioprintingDermisEpidermisFibroblastsKeratinocytesAdultAmputeesCell DifferentiationCollagenElastinFemaleHandHumansKeratin-9MaleCollagenElastinKeratin-9KRT9 protein, human
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.