Evidence map›Paper›PMID 39236238›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Single-molecule force spectroscopy reveals intra- and intermolecular interactions of

Shimin Le, Miao Yu, Chaoyu Fu, Jonathon A Heier, Sterling Martin, Jeff Hardin, Jie Yan

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Force-dependent structural dynamics of the giant nesprin-2.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shimin Le *Mechanobiology Institute, National University of Singapore, Singapore 117411, Singapore.ORCID 0000-0003-2359-1897
Miao Yu *Department of Biochemistry and Division of Orthopaedic Surgery of the Second Affiliated Hospital, Zhejiang University, Hangzhou 310058, China.
Chaoyu Fu *Mechanobiology Institute, National University of Singapore, Singapore 117411, Singapore.
Jonathon A HeierDepartment of Integrative Biology, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0002-4898-0357
Sterling MartinBiophysics Program, University of Wisconsin-Madison, Madison, WI 53706.
Jeff HardinDepartment of Integrative Biology, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0001-7399-6580
Jie YanMechanobiology Institute, National University of Singapore, Singapore 117411, Singapore.ORCID 0000-0002-8555-7291

Funding

Tension-dependent regulation of alpha-catenin during morphogenesis in C. elegansR01GM058038 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HARDIN, JEFFREY D · 1998 to 2021
$6.2M
Regulation of dynamic actin networks during epithelial morphogenesisR35GM145312 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Jeffrey D Hardin · 2022 to 2026
$3.0M
Ministry of Education - Singapore (MOE) MOET2EP50220-0015MOST | NSFC | Key Programme 12204389MOST | NSFC | Key Programme 32271367MOST | NSFC | Key Programme 32301094NIGMS NIH HHS R01 GM058038NIGMS NIH HHS R35 GM145312
6 · The paper itself

Abstract

The

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsMechanotransduction, CellularActin CytoskeletonAdherens Junctionsalpha CateninAnimalsCadherinsCytoskeletal ProteinsProtein BindingSingle Molecule Imagingalpha CateninCadherinsCaenorhabditis elegans ProteinsCytoskeletal ProteinsHMP-1 protein, C elegansHMP-2 protein, C elegansHMP-1HMP-2magnetic tweezerssalt bridges

Identifiers

PMID39236238
PMCPMC11406289

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.