Evidence mapPaperPMID 39237306Full record

ArticleAging2024

Poor sleep quality, dementia status and their association with all-cause mortality among older US adults.

May A Beydoun, Rio Tate, Michael F Georgescu, Alyssa A Gamaldo, Christian A Maino Vieytes, Hind A Beydoun, Nicole Noren Hooten, Michele K Evans, Alan B Zonderman

Abstract read
In one paragraph

Article in Aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

May A BeydounLaboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, NIA/NIH/IRP, Baltimore, MD 21224, USA.
Rio TateLaboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, NIA/NIH/IRP, Baltimore, MD 21224, USA.
Michael F GeorgescuLaboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, NIA/NIH/IRP, Baltimore, MD 21224, USA.
Alyssa A GamaldoDepartment of Psychology, Clemson University, Clemson, SC 29634, USA.
Christian A Maino VieytesLaboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, NIA/NIH/IRP, Baltimore, MD 21224, USA.
Hind A BeydounDepartment of Veterans Affairs, VA National Center on Homelessness Among Veterans, Washington, DC 20420, USA.
Nicole Noren HootenLaboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, NIA/NIH/IRP, Baltimore, MD 21224, USA.
Michele K EvansLaboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, NIA/NIH/IRP, Baltimore, MD 21224, USA.
Alan B ZondermanLaboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, NIA/NIH/IRP, Baltimore, MD 21224, USA.

Funding

Health and Retirement Study: Yrs 35-40U01AG009740 · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 1990 to 2025
$96.8M
Psychosocial and Neighborhood Mechanisms and Consequences of Black-White Sleep Disparities on CognitionU01AG072619 · CLEMSON UNIVERSITY · 2025 to 2025
$634k
Healthy Aging Neighborhoods of Diversity Across LifespanZ01AG000513 · AGING · 2001 to 2005
Intramural NIH HHS Z01 AG000513NIA NIH HHS U01 AG009740NIA NIH HHS U01 AG072619NIA NIH HHS UF1 AG072619
6 · The paper itself

Abstract

backgroundEvidence points to associations between sleep quality, dementia, and mortality. We examined whether poor sleep quality mediated or moderated the association between dementia and mortality risk among older US adults and vice versa, and whether these associations differed by sex and by race.

methodsThe study investigated bi-directional associations between sleep quality, dementia and mortality in older US adults using data from the Health and Retirement Study (

resultsPoor sleep quality was associated with increased mortality risk, particularly among male and White older adults. However, the association was reversed in the fully adjusted model, with a 7% decrease in risk per tertile. Probable dementia was associated with a two-fold increase in mortality risk, with a stronger association found among White adults. The association was markedly attenuated in the fully adjusted models. Sleep quality-stratified models showed a stronger positive association between dementia and mortality among individuals with better sleep quality. Both mediation and interaction were involved in explaining the total effects under study, though statistically significant total effects were mainly composed of controlled direct effects.

conclusionsPoor sleep quality is directly related to mortality risk before lifestyle and health-related factors are adjusted. Dementia is linked to mortality risk, especially in individuals with better sleep quality, males, and White older adults. Future research should explore the underlying mechanisms.

Indexed as

DementiaSleep QualityAgedAged, 80 and overFemaleHumansMaleMortalityProportional Hazards ModelsRisk FactorsUnited Statesagingcohort studiesdementiamortalitysleep quality

Identifiers

PMID39237306
PMCPMC11424588

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.