ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2024
Symptom clusters and impact on quality of life in lung cancer patients undergoing chemotherapy.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Psychological capital in patients with cancer: A qualitative study based on cognitive adaptation theory.Asia-Pacific journal of oncology nursing · 2026Article
- Symptom clusters and quality of life among patients with thyroid cancer during early survivorship: a national multicenter cross-sectional study.The oncologist · 2026Article
- Neutrophil-to-Lymphocyte Ratio and MUST-Defined Nutritional Risk as Independent Correlates of Domain-Specific Quality of Life in Cancer Patients Receiving Chemotherapy.Journal of clinical medicine · 2026Article
- Prevalence of physical functional impairments and associations with quality of life: a cross-sectional study in Chinese cancer survivors.BMC nursing · 2026Article
- Health behaviors and symptom clusters mediate self-management efficacy and quality of life in lung cancer immunotherapy.Scientific reports · 2026Article
- Early chemotherapy symptom clusters predict quality of life and treatment adherence in lung cancer patients.Discover oncology · 2026Article
- Hospital-to-home transitions of patients with lung cancer - a qualitative study of primary healthcare professionals' experiences.BMC nursing · 2026Article
- Malnutrition-related symptom clusters and quality of life in nasopharyngeal carcinoma patients during radiotherapy: a network analysis.BMC cancer · 2026Article
- Experiences of psychosomatic symptoms and self-management strategies among patients with advanced lung cancer undergoing chemotherapy: a qualitative study based on symptom management theory.Frontiers in public health · 2026Article
- Metabolic dysregulation associated with core symptom cluster in lung cancer patients undergoing chemotherapy.British journal of cancer · 2026Article
- Dynamic nutritional trajectories and deterioration risk in esophageal cancer radiotherapy: a prospective study.Frontiers in nutrition · 2026Article
- Symptom networks in breast cancer patients during chemotherapy and their impact on daily living status.Frontiers in oncology · 2026Article
- Effect of symptom clusters on quality of life in patients with head and neck cancer treated with radiotherapy: a cross-sectional study.Scientific reports · 2025Article
- Experiences of the fatigue-pain-sleep disturbance symptom cluster among patients with lung cancer: A descriptive qualitative study.Asia-Pacific journal of oncology nursing · 2025Article
- Prevalence and associated factors of cognitive frailty in older patients with lung cancer undergoing chemotherapy: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- State of the "Art" in Precision Health Symptom Science Research.Seminars in oncology nursing · 2025Review
- Network analysis used to investigate the symptoms of cancer patients during chemotherapy: a scoping review.Discover oncology · 2025Review
- Effects of evidence-based nursing under a quantitative assessment strategy on cancer-related fatigue, self-management ability, and quality of life in lung cancer patients undergoing chemotherapy.Frontiers in oncology · 2025Article
- Contemporaneous symptom networks for multidimensional symptom experience in lung cancer survivors of immunotherapy: A network analysis.PloS one · 2025Article
- Pulmonary rehabilitation improves lung function and exercise tolerance in elderly non-surgical NSCLC patients.American journal of cancer research · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
purposeTo identify symptom clusters (SCs) in lung cancer patients undergoing chemotherapy and explore their impact on health-related quality of life (HRQoL).
methodsPatients were invited to complete the Chinese version of the M.D. Anderson Symptom Inventory with the Lung Cancer Module and the Quality of Life Questionnaire-core 30. Network analysis was employed to identify SCs. The associations between SCs and each function of HRQoL were examined using the Pearson correlation matrix. Multiple linear regression was applied to analyze the influencing factors of each function of HRQoL.
resultsA total of 623 lung cancer patients who were receiving chemotherapy were recruited. The global health status of lung cancer patients was 59.71 ± 21.09, and 89.73% of patients developed symptoms. Three SCs (Somato-psychological SC, Respiratory SC, and Gastrointestinal SC) were identified, and Somato-psychological SC and Gastrointestinal SC were identified as influencing factors for HRQoL in lung cancer patients.
conclusionMost lung cancer patients who undergo chemotherapy experience a range of symptoms, which can be categorized into three SCs. The Somato-psychological SC and Gastrointestinal SC negatively impacted patients' HRQoL. Health care providers should prioritize monitoring these SCs to identify high-risk patients early and implement targeted preventive and intervention measures for each SC, aiming to alleviate symptom burden and enhance HRQoL.
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