Evidence map›Paper›PMID 39243326›Full record

ReviewDiscover nano2024

Enhanced drug delivery with nanocarriers: a comprehensive review of recent advances in breast cancer detection and treatment.

Ruby Dhiman, Nancy Bazad, Riya Mukherjee, Himanshu, Gunjan, Elcio Leal, Saheem Ahmad, Kirtanjot Kaur, V Samuel Raj, Chung-Ming Chang and 1 more

Abstract readReview
In one paragraph

Review in Discover nano, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ruby DhimanCentre for Drug Design Discovery and Development (C4D), SRM University, Delhi-NCR, Rajiv Gandhi Education City, Sonepat, Haryana, India.
Nancy BazadCentre for Drug Design Discovery and Development (C4D), SRM University, Delhi-NCR, Rajiv Gandhi Education City, Sonepat, Haryana, India.
Riya MukherjeeDepartment in Biotechnology Industry, Chang Gung University, Taoyuan City, Taiwan, ROC.
HimanshuDepartment in Biotechnology Industry, Chang Gung University, Taoyuan City, Taiwan, ROC.
GunjanDepartment in Biotechnology Industry, Chang Gung University, Taoyuan City, Taiwan, ROC.
Elcio LealLaboratório de Diversidade Viral, Instituto de Ciências Biológicas, Universidade Federal Do Pará, Belem, Pará, Brazil.
Saheem AhmadDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Hail, Hail City, Kingdom of Saudi Arabia.
Kirtanjot KaurUniversity Centre for Research and Development, Chandigarh University, Mohali, Punjab, India.
V Samuel RajCentre for Drug Design Discovery and Development (C4D), SRM University, Delhi-NCR, Rajiv Gandhi Education City, Sonepat, Haryana, India.
Chung-Ming ChangDepartment in Biotechnology Industry, Chang Gung University, Taoyuan City, Taiwan, ROC. cmchang@mail.cgu.edu.tw.
Ramendra Pati PandeySchool of Health Sciences and Technology (SOHST), UPES, Dehradun, Uttarakhand, 248007, India. ramendra.pandey@ddn.upes.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BC) remains a leading cause of morbidity and mortality among women worldwide, with triple-negative breast cancer (TNBC) posing significant treatment challenges due to its aggressive phenotype and resistance to conventional therapies. Recent advancements in nanocarrier technology offer promising solutions for enhancing drug delivery, improving bioavailability, and increasing drug accumulation at tumor sites through targeted approaches. This review delves into the latest innovations in BC detection and treatment, highlighting the role of nanocarriers like polymeric micelles, liposomes, and magnetic nanoparticles in overcoming the limitations of traditional therapies. Additionally, the manuscript discusses the integration of cutting-edge diagnostic tools, such as multiplex PCR-Nested Next-Generation Sequencing (mPCR-NGS) and blood-based biomarkers, which are revolutionizing early detection and molecular profiling of BC. The convergence of these technologies not only enhances therapeutic outcomes but also paves the way for personalized medicine in BC management. This comprehensive review underscores the potential of nanocarriers in transforming BC treatment and emphasizes the critical importance of early detection in improving patient prognosis.

Indexed as

Breast cancerDiagnosticNanocarriersTumor location

Identifiers

PMID39243326
PMCPMC11380656

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.