Evidence mapPaperPMID 39245437Full record

ArticleAutophagy2025

Targeted proteomics addresses selectivity and complexity of protein degradation by autophagy.

Alexandre Leytens, Rocío Benítez-Fernández, Carlos Jiménez-García, Carole Roubaty, Michael Stumpe, Patricia Boya, Jörn Dengjel

Abstract read
In one paragraph

Article in Autophagy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexandre LeytensDepartment of Biology, University of Fribourg, Fribourg, Switzerland.
Rocío Benítez-FernándezDepartment of Neuroscience and Movement Science, University of Fribourg, Fribourg, Switzerland.
Carlos Jiménez-GarcíaDepartment of Neuroscience and Movement Science, University of Fribourg, Fribourg, Switzerland.
Carole RoubatyDepartment of Biology, University of Fribourg, Fribourg, Switzerland.
Michael StumpeDepartment of Biology, University of Fribourg, Fribourg, Switzerland.
Patricia BoyaDepartment of Neuroscience and Movement Science, University of Fribourg, Fribourg, Switzerland.ORCID 0000-0003-3045-951X
Jörn DengjelDepartment of Biology, University of Fribourg, Fribourg, Switzerland.ORCID 0000-0002-9453-4614

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macroautophagy/autophagy is a constitutively active catabolic lysosomal degradation pathway, often found dysregulated in human diseases. It is often considered to act in a cytoprotective manner and is commonly upregulated in cells undergoing stress. Its initiation is regulated at the protein level and does not require

Indexed as

AutophagyProteolysisProteomicsAutophagosomesHeLa CellsHumansLysosomesER-phagymass spectrometrymitophagyparallel reaction monitoringreticulophagyselective autophagy receptors

Identifiers

PMID39245437
PMCPMC11759517

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.