Evidence mapPaperPMID 39245669Full record

ArticleScientific reports2024

Influence of remnant cholesterol levels on carotid intima thickness in type 2 diabetes patients.

Rong Liu, Tao Xu, Ling Gan, Caihong Chang, Yao Peng, Wenlin Yao, Aihua Zhai, Ming Fang, Xinan Shang, Shuai Chang and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rong Liu *Department of Ultrasound, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, No 15, Jiefang Avenue, Xiangyang, 441000, Hubei, China.
Tao Xu *Department of Ultrasound, The Affiliated Yixing Hospital of Jiangsu University, 75 Tongzhenguan Road, Wuxi, 214200, Jiangsu, China.
Ling Gan *Department of Ultrasound, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, No 15, Jiefang Avenue, Xiangyang, 441000, Hubei, China.
Caihong Chang *Department of Ultrasound, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, No 15, Jiefang Avenue, Xiangyang, 441000, Hubei, China.
Yao PengDepartment of Ultrasound, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, No 15, Jiefang Avenue, Xiangyang, 441000, Hubei, China.
Wenlin YaoDepartment of Ultrasound, Xiangzhou District People's Hospital of Xiangyang, Xiangyang, 441199, Hubei, China.
Aihua ZhaiDepartment of Ultrasound, Xiangzhou District People's Hospital of Xiangyang, Xiangyang, 441199, Hubei, China.
Ming FangDepartment of Ultrasound, Xiangzhou District People's Hospital of Xiangyang, Xiangyang, 441199, Hubei, China.
Xinan ShangDepartment of Ultrasound, Xiangzhou District People's Hospital of Xiangyang, Xiangyang, 441199, Hubei, China.
Shuai ChangDepatment of Ultrasound, First Affiliated Hospital of University of South China, Hengyang, 421001, Hunan, China.
Jianfeng GuoDepartment of Ultrasound, The Affiliated Yixing Hospital of Jiangsu University, 75 Tongzhenguan Road, Wuxi, 214200, Jiangsu, China. staff752@yxph.com.
Jiaqi ZhangDepartment of Ultrasound, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, No 15, Jiefang Avenue, Xiangyang, 441000, Hubei, China. 347235272@qq.com.

Funding

Hubei Provincial Health Commission Research Project WJ2023F072Innovative Research Program of Xiangyang No.1 People's Hospital XYY2023QT03Key Projects in Xiangyang Medical and Health Field 2022YL26AKey Projects in Xiangyang Medical and Health Field 2022YL52BKey R&D Plan of Hubei Province 2022BCE004
6 · The paper itself

Abstract

Investigate the impact of remnant cholesterol (RC) levels on carotid artery intima thickness (CIT) in type 2 diabetes mellitus (T2DM) patients. From September 2021 to September 2023, a prospective multicenter study involved 158 T2DM patients. They were divided into a higher RC group (n = 80) and a lower RC group (n = 78) based on median RC levels. Additionally, 92 healthy volunteers served as the control group. CIT, carotid media thickness (CMT), and carotid intima-media thickness (CIMT) were measured. General clinical data, lab results, CIMT, CIT, and CMT differences among the three groups were compared. Multiple regression analysis explored CIT factors in T2DM patients. 1. No significant sex, age, BMI, high-density lipoprotein cholesterol (HDL-C), T2DM duration, fasting blood glucose, or glycated hemoglobin differences were found among the groups (p > 0.05). 2. CIMT and CIT were significantly higher in T2DM than the control group (p < 0.05). 3. The higher RC group had thicker CIT than the lower RC group (p < 0.05), while CIMT differences were not significant (p > 0.05). Multiple linear regression analysis showed RC as an influencing CIT factor in T2DM patients (β = 0.473, p = 0.005). CIT is significantly thicker in T2DM patients with higher RC than in those with lower RC, and RC is the influence factor of CIT, which suggests that more attention should be paid to the detection of RC in T2DM patients.

Indexed as

Carotid Intima-Media ThicknessCholesterolDiabetes Mellitus, Type 2AdultAgedCase-Control StudiesFemaleHumansMaleMiddle AgedProspective StudiesRisk FactorsCholesterolCarotid intima thicknessHigh-frequency ultrasoundRemnant cholesterolType 2 diabetes

Identifiers

PMID39245669
PMCPMC11381536

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.