SynthesisBrain imaging and behavior2024
Resting-state functional abnormalities in ischemic stroke: a meta-analysis of fMRI studies.
Synthesis in Brain imaging and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- AES-SDM meta-analysis of spontaneous brain activity in cerebral small vessel disease.BMC medical imaging · 2026Pooled it
- A systematic review and coordinate-based meta-analysis of resting-state fMRI in athletes from open and closed skills sports.Scientific reports · 2025Pooled it
- Enhanced hippocampal-cortical functional connectivity following post-stroke cognitive impairment: a resting-state functional magnetic resonance imaging study.Quantitative imaging in medicine and surgery · 2026Article
- Topological Alterations of Functional Brain Networks in Post-Stroke Cognitive Impairment: a Graph-Theoretical Study.Clinical neuroradiology · 2026Article
- White Matter Infarct Detection with Transformer and Auto-ML-Derived Models.Brain sciences · 2026Article
- Motor-related reorganization in left inferior frontal gyrus after subcortical stroke: neurochemical basis and response to targeted neuromodulation.BMC medicine · 2026Article
- Hemispheric disparity theory: a dual-system framework for consciousness.Frontiers in psychology · 2026Article
- White Matter Microstructural Injury in Patients With Acute Single Subcortical Infarction: A Preliminary Tract-Based Spatial Statistics With Atlas-Based Analysis.Neural plasticity · 2026Article
- Resting-State Functional MRI Analyses for Brain Activity Characterization: A Narrative Review of Features and Methods.The European journal of neuroscience · 2025Review
- Resting-State Functional Connectivity of Sensorimotor and Default Mode Networks and Lower Limb Performance in Chronic Stroke: A Cross-Sectional Study.Brain and behavior · 2025Article
- Effects of intermittent theta burst stimulation on upper limb motor recovery in early stroke patients: an fNIRS study.Frontiers in neurology · 2025Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ischemic stroke is a leading neurological cause of severe disabilities and death in the world and has a major negative impact on patients' quality of life. However, the neural mechanism of spontaneous fluctuating neuronal activity remains unclear. This meta-analysis explored brain activity during resting state in patients with ischemic stroke including 22 studies of regional homogeneity, amplitude of low-frequency fluctuation, and fractional amplitude of low-frequency fluctuation (692 patients with ischemic stroke, 620 healthy controls, age range 35-80 years, 41% female, 175 foci). Results showed decreased regional activity in the bilateral caudate and thalamus and increased regional activity in the left superior occipital gyrus and left default mode network (precuneus/posterior cingulate cortex). Meta-analysis of the amplitude of low-frequency fluctuation studies showed that increased activity in the left inferior frontal gyrus was reduced across the progression from acute to chronic phases. These findings may indicate that disruption of the subcortical areas and default mode network could be one of the core functional abnormalities in ischemic stroke. Altered brain activity in the inferior frontal gyrus could be the imaging indicator of brain recovery/plasticity after stroke damage, which offers potential insight into developing prediction models and therapeutic strategies for ischemic stroke rehabilitation and recovery.
Indexed as
Identifiers
39245741What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.