Evidence map›Paper›PMID 39246195›Full record

ReviewSmall (Weinheim an der Bergstrasse, Germany)2024

Periodic Flows in Microfluidics.

Amith Mudugamuwa, Uditha Roshan, Samith Hettiarachchi, Haotian Cha, Hafiz Musharaf, Xiaoyue Kang, Quang Thang Trinh, Huan Ming Xia, Nam-Trung Nguyen, Jun Zhang

Abstract readReview
In one paragraph

Review in Small (Weinheim an der Bergstrasse, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Periodic Flows in Microfluidics.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amith MudugamuwaQueensland Micro and Nanotechnology Centre, Griffith University, Brisbane, QLD, 4111, Australia.
Uditha RoshanQueensland Micro and Nanotechnology Centre, Griffith University, Brisbane, QLD, 4111, Australia.
Samith HettiarachchiQueensland Micro and Nanotechnology Centre, Griffith University, Brisbane, QLD, 4111, Australia.
Haotian ChaQueensland Micro and Nanotechnology Centre, Griffith University, Brisbane, QLD, 4111, Australia.
Hafiz MusharafQueensland Micro and Nanotechnology Centre, Griffith University, Brisbane, QLD, 4111, Australia.
Xiaoyue KangQueensland Micro and Nanotechnology Centre, Griffith University, Brisbane, QLD, 4111, Australia.
Quang Thang TrinhQueensland Micro and Nanotechnology Centre, Griffith University, Brisbane, QLD, 4111, Australia.
Huan Ming XiaSchool of Mechanical Engineering, Nanjing University of Science and Technology, Nanjing, 210094, P. R. China.
Nam-Trung NguyenQueensland Micro and Nanotechnology Centre, Griffith University, Brisbane, QLD, 4111, Australia.
Jun ZhangQueensland Micro and Nanotechnology Centre, Griffith University, Brisbane, QLD, 4111, Australia.ORCID 0000-0003-1113-6264

Funding

ARC DECRA fellowship DE210100692Australian Research Council FL230100023Australian Research Council FT240100020
6 · The paper itself

Abstract

Microfluidics, the science and technology of manipulating fluids in microscale channels, offers numerous advantages, such as low energy consumption, compact device size, precise control, fast reaction, and enhanced portability. These benefits have led to applications in biomedical assays, disease diagnostics, drug discovery, neuroscience, and so on. Fluid flow within microfluidic channels is typically in the laminar flow region, which is characterized by low Reynolds numbers but brings the challenge of efficient mixing of fluids. Periodic flows are time-dependent fluid flows, featuring repetitive patterns that can significantly improve fluid mixing and extend the effective length of microchannels for submicron and nanoparticle manipulation. Besides, periodic flow is crucial in organ-on-a-chip (OoC) for accurately modeling physiological processes, advancing disease understanding, drug development, and personalized medicine. Various techniques for generating periodic flows have been reported, including syringe pumps, peristalsis, and actuation based on electric, magnetic, acoustic, mechanical, pneumatic, and fluidic forces, yet comprehensive reviews on this topic remain limited. This paper aims to provide a comprehensive review of periodic flows in microfluidics, from fundamental mechanisms to generation techniques and applications. The challenges and future perspectives are also discussed to exploit the potential of periodic flows in microfluidics.

Indexed as

MicrofluidicsHumansLab-On-A-Chip Deviceshydraulic‐electric analogyoscillatory flowsperiodic flow generationpulsatile flows

Identifiers

PMID39246195
PMCPMC11636114

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.