Evidence map›Paper›PMID 39248327›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Cell Identity and Spatial Distribution of PD-1/PD-L1 Blockade Responders.

Xintong Li, Yuanxin Liu, Jun Gui, Lu Gan, Jianxin Xue

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Tumor-embedded Immunity and TRM Cell Functions in Cancer.Mini reviews in medicinal chemistry · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Cell Identity and Spatial Distribution of PD-1/PD-L1 Blockade Responders.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xintong LiDivision of Thoracic Tumor Multimodality Treatment, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, China.ORCID 0000-0003-2864-3430
Yuanxin LiuDivision of Thoracic Tumor Multimodality Treatment, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, China.
Jun GuiState Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Lu GanResearch Laboratory of Emergency Medicine, Department of Emergency Medicine, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, China.
Jianxin XueDivision of Thoracic Tumor Multimodality Treatment, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, Laboratory of Clinical Cell Therapy, West China Hospital, Sichuan University, Chengdu, 610041, China.ORCID 0000-0003-4501-7538

Funding

Beijing Xisike Clinical Oncology Research Foundation Y-HS202202-0094Bethune · Cancer Radiotherapy Translational Medicine Research Foundation flzh202110National Natural Science Foundation of China 82373021Science and Technology Department of Sichuan Province 23ZYZYTS0154Science and Technology Department of Sichuan Province QC1000West China Hospital, Sichuan University ZYYC23008West China Hospital, Sichuan University ZYYC23010
6 · The paper itself

Abstract

The programmed death 1 (PD-1)/programmed death ligand 1 (PD-L1) axis inhibits T cell activity, impairing anti-tumor immunity. Blocking this axis with therapeutic antibodies is one of the most promising anti-tumor immunotherapies. It has long been recognized that PD-1/PD-L1 blockade reinvigorates exhausted T (T

Indexed as

B7-H1 AntigenImmune Checkpoint InhibitorsNeoplasmsProgrammed Cell Death 1 ReceptorTumor MicroenvironmentHumansImmunotherapyT-LymphocytesB7-H1 AntigenCD274 protein, humanImmune Checkpoint InhibitorsProgrammed Cell Death 1 Receptorcancercell therapyimmunotherapyPD‐1/PD‐L1 blockadesstem‐like T‐cellsT‐cell exhaustion

Identifiers

PMID39248327
PMCPMC11538707

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.