Evidence map›Paper›PMID 39248486›Full record

ArticleInfection and immunity2024

Eosinophils respond to, but are not essential for control of an acute

Rachael D FitzPatrick, Jonathan R Noone, Richard A Cartwright, Dominique M Gatti, Tara P Brosschot, Jenna M Lane, Erik L Jensen, Isabella Kroker Kimber, Lisa A Reynolds

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Tissue adaptation of eosinophils.Journal of leukocyte biology · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rachael D FitzPatrickDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada.ORCID 0000-0001-7940-1955
Jonathan R NooneDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada.
Richard A CartwrightDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada.
Dominique M GattiDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada.
Tara P BrosschotDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada.
Jenna M LaneDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada.
Erik L JensenDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada.
Isabella Kroker KimberDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada.
Lisa A ReynoldsDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada.ORCID 0000-0002-2969-2296

Funding

Canadian Government | Canadian Institutes of Health Research (CIHR) 156403Michael Smith Foundation for Health Research SCH-2021-1582
6 · The paper itself

Abstract

Eosinophils are a highly abundant cell type in the gastrointestinal tract during homeostatic conditions, where they have recently been reported to take on an activated phenotype following colonization by the bacterial microbiota. To date, there have been few studies investigating whether eosinophils respond to infection with enteric bacterial pathogens and/or investigating the requirements for eosinophils for effective bacterial pathogen control. In this study, we investigated the response of eosinophils to an acute enteric infection of mice with the bacterial pathogen

Indexed as

EosinophilsMice, Inbred BALB CSalmonella Infections, AnimalSalmonella typhimuriumAnimalsBacterial LoadDisease Models, AnimalFemaleLymph NodesMiceSalmonella Infectionsacute bacterial infectioneosinophil–bacteria interactionseosinophilsflow cytometrygut inflammationintestinal tractmouse infection modelsSalmonella

Identifiers

PMID39248486
PMCPMC11475665

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.