Evidence map›Paper›PMID 39250296›Full record

ReviewBehavioral neuroscience2024

Modeling impaired insight after drug use in rodents.

Marios Chris Panayi, Geoffrey Schoenbaum

Abstract readReview
In one paragraph

Review in Behavioral neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marios Chris PanayiNational Institute on Drug Abuse Intramural Research Program.ORCID 0000-0003-2635-5638
Geoffrey SchoenbaumNational Institute on Drug Abuse Intramural Research Program.ORCID 0000-0001-8180-0701

Funding

Associative learning, decision-making, and addictionZIADA000587 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI SCHOENBAUM, GEOFFREY · 2012 to 2025
$47.7M
Intramural NIH HHS ZIA DA000587NIDA NIH HHS
6 · The paper itself

Abstract

Impaired insight in substance use disorder has been argued to reflect a global deficit in using cognitive models to mentally simulate possible future outcomes. The process of mentally simulating outcomes allows us to understand our beliefs about their causes, that is, to have insight and thereby avoid potentially negative outcomes. However, work in humans cannot address whether impaired insight and its neural/neurochemical sequalae are present prior to the development of a substance use disorder, a consequence of substance use, or a combination of both. This is because baseline measurements prior to drug use are not possible in humans. However, if these changes can be directly caused by drug use, then in animal models, a history of drug use should cause impairments in behavioral tasks designed to assess such inferences. Focusing on cocaine use, here we will review several lines of research from our laboratory that have tested this question using learning-theory tasks designed to isolate insight. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Indexed as

Substance-Related DisordersAnimalsDisease Models, AnimalHumansLearningRatsRodentia

Identifiers

PMID39250296
PMCPMC11874615

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.