Evidence map›Paper›PMID 39251824›Full record

ArticleScientific reports2024

The usage of immunosuppressant agents and secondary infections in patients with COVID-19 in the intensive care unit: a retrospective study.

Zeynep Tugce Sarikaya, Bulent Gucyetmez, Filiz Tuzuner, Ozlem Dincer, Cenk Sahan, Lerzan Dogan, Serap Aktas Yildirim, Rehile Zengin, Ayse Sesin Kocagoz, Lutfi Telci and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zeynep Tugce SarikayaDepartment of Anesthesiology and Reanimation, Acibadem Mehmet Ali Aydinlar University School of Medicine, Istanbul, Turkey. tugcesrky@gmail.com.ORCID 0000-0002-1352-7667
Bulent GucyetmezDepartment of Anesthesiology and Reanimation, Acibadem Mehmet Ali Aydinlar University School of Medicine, Istanbul, Turkey.ORCID 0000-0003-0987-7995
Filiz TuzunerGeneral Intensive Care Unit, Acibadem Taksim Hospital, Istanbul, Turkey.ORCID 0000-0002-3082-9069
Ozlem DincerGeneral Intensive Care Unit, Acibadem Atakent Hospital, Istanbul, Turkey.ORCID 0000-0003-4471-0541
Cenk SahanGeneral Intensive Care Unit, Acibadem Atakent Hospital, Istanbul, Turkey.ORCID 0000-0003-4253-5989
Lerzan DoganGeneral Intensive Care Unit, Acibadem Altunizade Hospital, Istanbul, Turkey.ORCID 0000-0002-1456-4072
Serap Aktas YildirimDepartment of Anesthesiology and Reanimation, Acibadem Mehmet Ali Aydinlar University School of Medicine, Istanbul, Turkey.ORCID 0000-0002-4889-6649
Rehile ZenginDepartment of Infectious Diseases and Clinical Microbiology, Acibadem Altunizade Hospital, Istanbul, Turkey.ORCID 0000-0001-7457-0952
Ayse Sesin KocagozDepartment of Infectious Disease and Clinical Microbiology, Acibadem Mehmet Ali Aydinlar University School of Medicine, Istanbul, Turkey.ORCID 0000-0002-9599-7629
Lutfi TelciGeneral Intensive Care Unit, Acibadem International Hospital, Istanbul, Turkey.ORCID 0000-0001-6838-5670
Ibrahim Ozkan AkinciGeneral Intensive Care Unit, Acibadem Altunizade Hospital, Istanbul, Turkey.ORCID 0000-0003-1657-3869

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although COVID-19 infection is an immunosuppressant disease, many immunosuppressant agents, such as pulse methylprednisolone (PMP), dexamethasone (DXM), and tocilizumab (TCZ), were used during the pandemic. Secondary infections in patients with COVID-19 have been reported recently. This study investigated these agents' effects on secondary infections and outcomes in patients with COVID-19 in intensive care units (ICUs). This study was designed retrospectively, and all data were collected from the tertiary intensive care units of six hospitals between March 2020 and October 2021. All patients were divided into three groups: Group I [GI, PMP (-), DXM (-) and TCZ (-)], Group II [GII, PMP (+), DXM (+)], and Group III [GIII, PMP (+), DXM (+), TCZ (+)]. Demographic data, P

Indexed as

COVID-19Immunosuppressive AgentsIntensive Care UnitsAdultAgedAntibodies, Monoclonal, HumanizedCOVID-19 Drug TreatmentDexamethasoneFemaleHumansMaleMethylprednisoloneMiddle AgedRetrospective StudiesSARS-CoV-2Antibodies, Monoclonal, HumanizedDexamethasoneImmunosuppressive AgentsMethylprednisolonetocilizumabCOVID-19 infectionDexamethasoneImmunosuppressantIntensive care unitInterleukinMethylprednisolonePandemicPropensity score matchingRetrospectivelySecondary

Identifiers

PMID39251824
PMCPMC11385116

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.