Evidence map›Paper›PMID 39252074›Full record

ReviewChinese medicine2024

Application of omics technologies in studies on antitumor effects of Traditional Chinese Medicine.

Peng Tan, Xuejiao Wei, Huiming Huang, Fei Wang, Zhuguo Wang, Jinxin Xie, Longyan Wang, Dongxiao Liu, Zhongdong Hu

Abstract readReview
In one paragraph

Review in Chinese medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Peng TanSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100029, China.
Xuejiao WeiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100029, China.
Huiming HuangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100029, China.
Fei WangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100029, China.
Zhuguo WangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100029, China.
Jinxin XieSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100029, China.
Longyan WangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100029, China.
Dongxiao LiuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100029, China.
Zhongdong HuModern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China. zdhu@bucm.edu.cn.ORCID http://orcid.org/0000-0003-4849-3353

Funding

Beijing Natural Science Foundation J230034Fundamental Research Funds for the Central Universities 2023-JYB-JBQN-051National Natural Science Foundation of China 81873044National Natural Science Foundation of China 82074072Talent Cultivation Project of Beijing University of Chinese Medicine JZPY202206
6 · The paper itself

Abstract

Traditional Chinese medicine (TCM) is considered to be one of the most comprehensive and influential form of traditional medicine. It plays an important role in clinical treatment and adjuvant therapy for cancer. However, the complex composition of TCM presents challenges to the comprehensive and systematic understanding of its antitumor mechanisms, which hinders further development of TCM with antitumor effects. Omics technologies can immensely help in elucidating the mechanism of action of drugs. They utilize high-throughput sequencing and detection techniques to provide deeper insights into biological systems, revealing the intricate mechanisms through which TCM combats tumors. Multi-omics approaches can be used to elucidate the interrelationships among different omics layers by integrating data from various omics disciplines. By analyzing a large amount of data, these approaches further unravel the complex network of mechanisms underlying the antitumor effects of TCM and explain the mutual regulations across different molecular levels. In this study, we presented a comprehensive overview of the recent progress in single-omics and multi-omics research focused on elucidating the mechanisms underlying the antitumor effects of TCM. We discussed the significance of omics technologies in advancing research on the antitumor properties of TCM and also provided novel research perspectives and methodologies for further advancing this research field.

Indexed as

AntitumorMechanism investigationOmics technologiesTraditional Chinese Medicine

Identifiers

PMID39252074
PMCPMC11385818

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.