Evidence map›Paper›PMID 39254792›Full record

ReviewCell biochemistry and biophysics2025

Revolutionizing Diabetes Care: The Role of Marine Bioactive Compounds and Microorganisms.

Konatham Teja Kumar Reddy, Kamsali Rakesh, Segu Prathyusha, Jeetendra Kumar Gupta, Kasturi Nagasree, R Lokeshvar, Selvaraja Elumalai, P Dharani Prasad, Deepti Kolli

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cell biochemistry and biophysics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Antidiabetic Effects ofMarine drugs · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Konatham Teja Kumar ReddyDepartment of Pharmacy, University College of Technology, Osmania University, Amberpet, Hyderabad, Telangana, India.
Kamsali RakeshDepartment of Chemistry, Koneru Lakshmaiah Education Foundation, Greenfields, Vaddeswaram, Guntur, Andhra Pradesh, India.
Segu PrathyushaDepartment of Pharmacognosy, School of Pharmacy, Guru Nanak Institutions Technical Campus, Hyderabad, India.
Jeetendra Kumar GuptaDepartment of Pharmacology, Institute of Pharmaceutical Research, GLA University, Mathura, Chaumuhan, Uttar Pradesh, India.
Kasturi NagasreeDepartment of Regulatory Affairs, Samskruthi College of Pharmacy Samskruti College of Pharmacy, Ghatkesar, Telangana, India.
R LokeshvarDepartment of Pharmacology, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences, Saveetha Nagar, Thandalam, Chennai, India.
Selvaraja ElumalaiDepartment of Quality Control, Ambiopharm Inc, Dittman Ct, Beach Island, South Carolina, 29842, USA.
P Dharani PrasadDepartment of Pharmacology, Mohan Babu University, MB School of Pharmaceutical Sciences, (Erstwhile, Sree Vidyaniketan College of Pharmacy), Tirupati, India.
Deepti KolliDepartment of Chemistry, Koneru Lakshmaiah Education Foundation, Greenfields, Vaddeswaram, Guntur, Andhra Pradesh, India. atluri.deepti1984@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes is a metabolic condition characterized by high blood glucose levels. Aquatic products like microalgae, bacteria, seagrasses, macroalgae, corals, and sponges have been investigated for potential anti-diabetic properties. We looked at polyphenols, peptides, pigments, and sterols, as well as other bioactive substances found in marine resources, to see if they could help treat or manage diabetes, in addition to describing the several treatment strategies that alter diabetes and its implications, such as inhibition of protein tyrosine phosphatases 1B (PTP1B), α-glucosidase, α-amylase, dipeptidyl peptidase IV (DPP-IV), aldose reductase, lipase, glycogen synthase kinase 3β (GSK-3β), and insulin resistance prevention, promotion of liver antioxidant capacity, natural killer cell stimulant, anti-inflammatory actions, increased AMP-activated protein kinase (AMPK) phosphorylation and sugar and metabolism of the lipid, reducing oxidative stress, and β-pancreatic cell prevention. This study highlights the revolutionary potential of marine bioactive compounds and microorganisms in transforming diabetes care. We believe in a future in which innovative, sustainable, and efficient therapeutic approaches will result in improved quality of life and better outcomes for people with diabetes mellitus by forging a new path for treatment, utilizing the power of the world's oceans, and capitalizing on the symbiotic relationship between humans and the marine ecosystem. This study area offers optimism and promising opportunities for transforming diabetes care.

Indexed as

Aquatic OrganismsDiabetes MellitusHypoglycemic AgentsAnimalsHumansHypoglycemic AgentsAntidiabetic compoundsDiabetesMarine-derived productsMarine organismsMicroalga

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.