Evidence map›Paper›PMID 39255973›Full record

GuidelineRheumatology (Oxford, England)2024

The 2024 British Society for Rheumatology guideline for management of systemic sclerosis.

Christopher P Denton, Enrico De Lorenzis, Elen Roblin, Nina Goldman, Begonya Alcacer-Pitarch, Emma Blamont, Maya H Buch, Maresa Carulli, Caroline Cotton, Francesco Del Galdo and 20 more

Registry-linked trialAbstract readPractice Guideline
In one paragraph

Guideline in Rheumatology (Oxford, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07768644 (Nailfold Capillaroscopy in PH), which is not on this map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07768644 recruitingnot on this mapstarted 2026, after this paper: background citation

Nailfold Capillaroscopy in PH: Are Nailfold Changes Reversible With Pulmonary Vasodilator Therapy?

TypeobservationalSponsorUniversity of GlasgowRan2026 to 2028Enrolled60ConditionsPulmonary Arterial Hypertension (PAH) (WHO Group 1 PH), Pulmonary Hypertension (World Health Organization Group 3), Chronic Thromboembolic Pulmonary HypertensionArmsStandard of Care therapy
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
  9. Article
  10. Article
  11. Systemic sclerosis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Christopher P DentonDivision of Medicine, University College London, London, UK.ORCID 0000-0003-3975-8938
Enrico De LorenzisLeeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.ORCID 0000-0001-9819-105X
Elen RoblinCentre for Rheumatology, Royal Free London NHS Foundation Trust, London, UK.
Nina GoldmanDivision of Medicine, University College London, London, UK.
Begonya Alcacer-PitarchLeeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.ORCID 0000-0002-2208-444X
Emma BlamontScleroderma and Raynaud's UK (SRUK), London, UK.
Maya H BuchDepartment of Rheumatology, University of Manchester, Manchester, UK.ORCID 0000-0002-8962-5642
Maresa CarulliDepartment of Rheumatology, Hammersmith Hospitals NHS Foundation Trust, London, UK.
Caroline CottonDepartment of Rheumatology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Francesco Del GaldoLeeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.ORCID 0000-0002-8528-2283
Emma Derrett-SmithDepartment of Rheumatology, University of Birmingham, Birmingham, UK.
Karen DouglasDepartment of Rheumatology, The Dudley Group NHS Foundation Trust, Dudley, UK.
Sue FarringtonScleroderma and Raynaud's UK (SRUK), London, UK.
Kim FligelstoneCentre for Rheumatology, Royal Free London NHS Foundation Trust, London, UK.
Luke GompelsDepartment of Rheumatology, Somerset NHS Foundation Trust, Taunton, UK.
Bridget GriffithsDepartment of Rheumatology, Freeman Hospital, Newcastle, UK.
Ariane HerrickDepartment of Rheumatology, University of Manchester, Manchester, UK.ORCID 0000-0003-4941-7926
Michael HughesDepartment of Rheumatology, University of Manchester, Manchester, UK.
Clare PainDepartment of Rheumatology, Alder Hey Childrens Hospital, Liverpool, UK.ORCID 0000-0003-4965-3259
Georgina PantanoLived Experience, London, UK.
John D PaulingDepartment of Rheumatology, North Bristol NHS Foundation Trust, Bristol, UK.ORCID 0000-0002-2793-2364
Athiveeraramapandian PrabuDepartment of Rheumatology, University of Birmingham, Birmingham, UK.
Nuala O'DonoghueDepartment of Dermatology, Northern Care Alliance, Salford Royal, UK.
Elisabetta A RenzoniInterstitial Lung Disease Unit, Royal Brompton NHS Foundation Trust, London, UK.
Jeremy RoyleDepartment of Rheumatology, University Hospitals NHS Foundation Trust, Leicester, UK.
Muditha SamaranayakaDepartment of Rheumatology, Northern Care Alliance, Salford Royal, UK.
Julia SpieringsDepartment of Rheumatology, University of Utrecht, Utrecht, Netherlands.
Aoife TynanCentre for Rheumatology, Royal Free London NHS Foundation Trust, London, UK.
Louise WarburtonPrimary Care Sciences, Keele University, Keele, UK.
Voon H OngDivision of Medicine, University College London, London, UK.ORCID 0000-0001-5474-0053

Funding

Astra ZenecaBoehringer IngelheimBritish Society for RheumatologyVersus Arthritis 22398
6 · The paper itself

Abstract

This guideline was developed according to the British Society for Rheumatology Guidelines Protocol by a Guideline Development Group comprising healthcare professionals with expertise in SSc and people with lived experience, as well as patient organization representatives. It is an update of the previous 2015 SSc guideline. The recommendations were developed and agreed by the group and are underpinned by published evidence, assessed by systematic literature review and reinforced by collective expert opinion of the group. It considers all aspects of SSc including general management, treatment of organ-based complications, including cardiopulmonary, renal and gastrointestinal tract manifestations, as well as broader impact of disease. Whilst it is focused on adults with SSc we expect that the guideline will be relevant to people of all ages and expert input and review by paediatric rheumatologists and other relevant specialists considered where the guideline was, or may not be, applicable to young people with SSc and juvenile-onset disease. In addition to providing guidance on disease assessment and management the full guideline also considers service organization within the National Health Service and future approaches to audit of the guideline. The lay summary that accompanies this abstract can be found in Supplemental information 1.

Indexed as

RheumatologyScleroderma, SystemicAdultHumansSocieties, MedicalUnited Kingdomguidelineinterstitial lung diseasemanagementsclerodermasystemic sclerosis

Identifiers

PMID39255973
PMCPMC11534099

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.