Evidence map›Paper›PMID 39256325›Full record

ArticleJournal of racial and ethnic health disparities2025

COVID-19 Disease and Chronic Health Outcomes Associated with Nicotine Use in a Great Plains Tribal Community: A Community-Based Study.

Anna Tillery, Rae O'Leary, Angela Aherrera, Jaylynn Farlee, Brittany Youpee, Erena S Hovhannisyan Romero, Miranda Cajero, Jacob Duran, Esther Erdei, Ana M Rule

Abstract read
In one paragraph

Article in Journal of racial and ethnic health disparities, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anna TilleryJohns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA. atiller2@jh.edu.ORCID 0000-0002-9688-962X
Rae O'LearyMissouri Breaks Industries Research Inc., Eagle Butte, SD, USA.
Angela AherreraJohns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Jaylynn FarleeMissouri Breaks Industries Research Inc., Eagle Butte, SD, USA.
Brittany YoupeeMissouri Breaks Industries Research Inc., Eagle Butte, SD, USA.
Erena S Hovhannisyan RomeroThe University of New Mexico Health Sciences Center College of Pharmacy, Albuquerque, NM, USA.
Miranda CajeroThe University of New Mexico Health Sciences Center College of Pharmacy, Albuquerque, NM, USA.
Jacob DuranThe University of New Mexico Health Sciences Center College of Pharmacy, Albuquerque, NM, USA.
Esther ErdeiThe University of New Mexico Health Sciences Center College of Pharmacy, Albuquerque, NM, USA.
Ana M RuleJohns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.

Funding

Targeted Research Training CoreT42OH008428 · OH · JOHNS HOPKINS UNIVERSITY · PI RAMACHANDRAN, GURUMURTHY · 2005 to 2025
$31.1M
Pilot Project ProgramP30ES032756 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI Christopher D Heaney · 2022 to 2026
$6.0M
The Exposure to Metals from E-Cigarettes (EMIT) StudyR01ES030025 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI RULE, ANA MARIA · 2018 to 2020
$1.5M
CRST COVID-19 - Wayakta HeR21ES033119 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI ERDEI, ESTHER · 2021 to 2022
$376k
Respiratory Effects, Metal and Aldehyde exposure from e-cigarette use in young adults (REMA)K99ES034507 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI AHERRERA, ANGELA · 2022 to 2023
$319k
Center for Tobacco Products K99ES034507NIEHS NIH HHS 1R21ES033119NIEHS NIH HHS K99 ES034507NIEHS NIH HHS P30 ES032756NIEHS NIH HHS R01 ES030025NIEHS NIH HHS R21 ES033119NIOSH CDC HHS T42 OH0008428NIOSH CDC HHS T42 OH008428
6 · The paper itself

Abstract

backgroundThe Cheyenne River Sioux Tribe (CRST) is affected by high nicotine use and disease burden. Understanding nicotine exposure is important to recognize what groups may be at higher risk for negative health outcomes, including COVID-19.

objectiveTo compare self-reported health outcomes and nicotine use between exclusive electronic cigarette (e-cig) users, users of combustible cigarettes, dual e-cig/cigarette users, and nonusers among adult residents on the CRST.

methodsThe CRST "COVID-19 - Wayakta He study" ("Are you on guard against COVID-19?") recruited 562 participants on the reservation who filled out a 97-item survey. Regression models were used to analyze nicotine exposure, demographic characteristics, and health outcomes.

resultsPrevalence of nicotine use among participants was 53%. Reported median puffs per day was 15 for e-cig, 100 for cigarette, and 20 for dual users (p < 0.001). The odds of having COVID-19 were lower for nicotine users compared to nonusers (p < 0.001). The odds of hypertension (p = 0.04) and high cholesterol (p = 0.03) were lower for nicotine users compared to nonusers. The proportional odds were higher for nicotine users for longer COVID-19 recovery time (p = 0.046) and lower for more severe COVID-19 infection (p = 0.001). SIGNIFICANCE: This study provides critical data on self-reported COVID-19, chronic disease outcomes, and exposure to commercial nicotine products. Results from this unique Tribal community-driven study with a large sample size (N = 562 participants from 289 households) will help understand the role that environmental exposures played on increased COVID-19 mortality, help target public health interventions, and inform Tribal public health policies on emergency preparedness and exposure analyses.

Indexed as

COVID-19Indians, North AmericanNicotineAdolescentAdultAgedChronic DiseaseElectronic Nicotine Delivery SystemsFemaleHumansMaleMiddle AgedSelf ReportYoung AdultNicotineEpidemiologyInhalation exposuresPersonal exposuresPopulation-based studiesVulnerable populations

Identifiers

PMID39256325
PMCPMC13189523

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.