Evidence map›Paper›PMID 39256768›Full record

ArticleBMC biology2024

Hypoxia and Foxn1 alter the proteomic signature of dermal fibroblasts to redirect scarless wound healing to scar-forming skin wound healing in Foxn1

Barbara Gawronska-Kozak, Sylwia Machcinska-Zielinska, Katarzyna Walendzik, Marta Kopcewicz, Mirva Pääkkönen, Joanna Wisniewska

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Barbara Gawronska-KozakInstitute of Animal Reproduction and Food Research, Polish Academy of Sciences, Ul. Tuwima 10, 10-748, Olsztyn, Poland. b.kozak@pan.olsztyn.pl.ORCID http://orcid.org/0000-0002-2006-8534
Sylwia Machcinska-ZielinskaInstitute of Animal Reproduction and Food Research, Polish Academy of Sciences, Ul. Tuwima 10, 10-748, Olsztyn, Poland.
Katarzyna WalendzikInstitute of Animal Reproduction and Food Research, Polish Academy of Sciences, Ul. Tuwima 10, 10-748, Olsztyn, Poland.
Marta KopcewiczInstitute of Animal Reproduction and Food Research, Polish Academy of Sciences, Ul. Tuwima 10, 10-748, Olsztyn, Poland.
Mirva PääkkönenTurku Bioscience Centre, University of Turku and Åbo Akademi University, Tykistökatu 6, Biocity 5 Floor, 20520, Turku, Finland.
Joanna WisniewskaInstitute of Animal Reproduction and Food Research, Polish Academy of Sciences, Ul. Tuwima 10, 10-748, Olsztyn, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFoxn1

resultsWe showed that hypoxic conditions and Foxn1 stimulation modified the proteome of Foxn1

conclusionsThe present data highlight the effect of hypoxia and Foxn1 on the protein profile and functionality of regenerative Foxn1

Indexed as

CicatrixFibroblastsForkhead Transcription FactorsWound HealingAnimalsHypoxiaHypoxia-Inducible Factor 1, alpha SubunitMiceMice, KnockoutProteomeProteomicsSkinForkhead Transcription FactorsHif1a protein, mouseHypoxia-Inducible Factor 1, alpha SubunitProteomeWhn proteinDermal fibroblastsFoxn1HypoxiaPai-1RegenerationSkin wound healing

Identifiers

PMID39256768
PMCPMC11389453

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.