Evidence mapPaperPMID 39257165Full record

ArticleJournal of primary care & community health

Association Between SARS-CoV-2 Vaccination and Development of Antinuclear Antibodies Among Students.

Karol Laskowski, Justyna Paszkiewicz, Dorota Plewik, Adam Szepeluk, Kamil K Hozyasz

Abstract read
In one paragraph

Article in Journal of primary care & community health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karol LaskowskiJohn Paul II University in Biała Podlaska, Poland.
Justyna PaszkiewiczJohn Paul II University in Biała Podlaska, Poland.
Dorota PlewikJohn Paul II University in Biała Podlaska, Poland.
Adam SzepelukJohn Paul II University in Biała Podlaska, Poland.
Kamil K HozyaszJohn Paul II University in Biała Podlaska, Poland.ORCID 0000-0001-8606-2509

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAntinuclear antibodies (ANA) are the hallmark of many connective tissue disorders (including lupus), which comprise roughly 5% to 10% of chronic debilitating diseases causing morbidity and mortality. In society, fear of these diseases increases illness-related uncertainty because the prognosis of progression is often difficult to determine and at least some symptoms fluctuate unpredictably. In the anti-vaccination movement, the question of the possible connection between vaccination and connective tissue disorders and other autoimmune diseases has grown to rank as an important argument for rejecting vaccination. In 2021, every fifth Polish first-degree nursing student decided to not be vaccinated against COVID-19.

objectiveThis study aimed to explore the prevalence of antinuclear antibodies in students vaccinated and unvaccinated against COVID-19. PARTICIPANTS AND

methodsA single university cross-sectional study was performed in a small academic centre in Poland, where 210 students were recruited in 2022. All the participants were screened for SARS-CoV-2 IgG and antinuclear antibodies.

resultsThe mean age of the students who rejected vaccination was higher than that of those who were vaccinated. Among nursing students, 30.0% of vaccinated and 58.3% of unvaccinated individuals had COVID-19. The frequency of antinuclear antibodies was 3 times lower in vaccinated students than in unvaccinated students (2/159 vs 2/51;

conclusionThe results of our study did not confirm the rationality of rejecting vaccinations against COVID-19 for fear of developing autoimmune diseases among healthy students.

Indexed as

Antibodies, AntinuclearCOVID-19COVID-19 VaccinesAdolescentAdultCross-Sectional StudiesFemaleHumansMalePolandSARS-CoV-2StudentsStudents, NursingVaccinationVaccination HesitancyYoung AdultAntibodies, AntinuclearCOVID-19 Vaccinesanti-nuclear antibodiesautoimmune diseasesCOVID-19 vaccinationnursing students

Identifiers

PMID39257165
PMCPMC11406642

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.