Evidence map›Paper›PMID 39258503›Full record

Trial reportExperimental physiology2026

Impact of a 12-week high-intensity interval training intervention on cardiac structure and function after COVID-19 at 12-month follow-up.

Iben Elmerdahl Rasmussen, Mathilde Løk, Cody Garett Durrer, Anna Agnes Lytzen, Frederik Foged, Vera Graungaard Schelde, Josephine Bjørn Budde, Rasmus Syberg Rasmussen, Emma Fredskild Høvighoff, Villads Rasmussen and 12 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Iben Elmerdahl RasmussenCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-6349-0308
Mathilde LøkDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-6750-5156
Cody Garett DurrerCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-0046-1494
Anna Agnes LytzenCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0009-0000-0553-9783
Frederik FogedCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-4815-6672
Vera Graungaard ScheldeCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.
Josephine Bjørn BuddeCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-8119-8036
Rasmus Syberg RasmussenCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-5892-7859
Emma Fredskild HøvighoffCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-6057-3327
Villads RasmussenCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-2540-1022
Mark LyngbækCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-1931-9658
Simon JønckCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-6828-9398
Rikke Krogh-MadsenCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-4914-2715
Birgitte LindegaardCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-5236-8427
Peter Godsk JørgensenDepartment of Cardiology, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-1217-8944
Lars KøberDepartment of Cardiology, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-6635-1466
Niels VejlstrupDepartment of Cardiology, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-5362-8593
Bente Klarlund PedersenCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-6508-6288
Mathias Ried-LarsenCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-8388-5291
Morten Asp Vonsild LundDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-2711-1259
Ronan M G BergCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-5757-9506
Regitse Højgaard ChristensenCentre for Physical Activity Research, University Hospital Copenhagen - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-5316-5341

Funding

Canadian Government | Canadian Institutes of Health Research (CIHR) MFE-176582Rigshospitalet N/ATrygFonden (Tryg Foundation) 101390TrygFonden (Tryg Foundation) 20045
6 · The paper itself

Abstract

In patients previously hospitalised for COVID-19, a 12-week high-intensity interval training (HIIT) intervention has previously been shown to increase left ventricular mass (LVM) immediately after the intervention. In the present study, we examined the effects of the same HIIT scheme on LVM, pulmonary diffusing capacity, symptom severity and functional capacity at 12-month follow-up. In this investigator-blinded, randomised controlled trial, 12 weeks of a supervised HIIT scheme (4 × 4 min, three times a week) was compared to standard care (control) in patients recently discharged from hospital due to COVID-19. At inclusion and at 12-month follow-up, LVM was assessed by cardiac magnetic resonance imaging (cMRI, primary outcome), while pulmonary diffusing capacity for carbon monoxide (D

Indexed as

COVID-19HeartHigh-Intensity Interval TrainingAgedFemaleFollow-Up StudiesHeart VentriclesHumansMagnetic Resonance ImagingMaleMiddle AgedPost-Acute COVID-19 SyndromePulmonary Diffusing CapacitySARS-CoV-2cardiac magnetic resonance imagingdiffusing capacityexercise capacityleft ventricular masslong‐COVIDrehabilitation

Identifiers

PMID39258503
PMCPMC13238539

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.