Evidence map›Paper›PMID 39258791›Full record

ArticlePeriodontology 20002025

Introduction and overview on Autogenous Platelet Concentrates.

Marc Quirynen, Anton Sculean, Juan Blanco, Hom-Lay Wang, Nikos Donos

Abstract read
In one paragraph

Article in Periodontology 2000, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marc QuirynenDepartment of Oral Health Sciences, KU Leuven & Dentistry (Periodontology), University Hospitals Leuven, Leuven, Belgium.ORCID 0000-0001-8253-3908
Anton SculeanDepartment of Periodontology, University of Bern, Bern, Switzerland.ORCID 0000-0003-2836-5477
Juan BlancoDepartment of Surgery (Stomatology, Unit of Periodontology), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.ORCID 0000-0001-9251-513X
Hom-Lay WangDepartment of Periodontics and Oral Medicine, The University of Michigan, School of Dentistry, Ann Arbor, Michigan, USA.ORCID 0000-0003-4238-1799
Nikos DonosInstitute of Dentistry, Centre for Oral Clinical Research, Barts and The London School of Medicine and Dentistry, Queen Mary University of London (QMUL), London, UK.ORCID 0000-0002-4117-9073

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This special issue on autologous platelet concentrates (APCs) provides clinicians with an overview on the current understanding of the use of these biomaterials for soft and hard tissue regeneration. The included papers summarize scientific evidence and the clinical findings, presented in simple tables that outline potential benefits including Patient Reported Outcome Measures (PROMs). This approach enables clinicians to assess clinical relevance and researchers to identify significant gaps in the literature. The first part provides a comprehensive summary of the basic science surrounding APC, with particular focus on their preparation methods. Clear recommendations are outlined, which are crucial for obtaining high-quality APCs, alongside an exploration of how APCs may influence both soft and hard tissue healing processes. Part 2 delves into the clinical evidence for the potential benefits of APCs across a range of applications: alveolar ridge preservation, sinus floor elevation, periodontal plastic surgery, guided tissue regeneration, guided bone regeneration, the healing of Medication-Related Osteonecrosis of the Jaw (MRONJ), and endodontic surgery. In the part 3, the discussion turns to the effects of APCs on the healing of extra-oral wounds, including diabetic foot ulcers, venous leg ulcers, pressure injuries, burns, and more. The fourth section offers a detailed, step-by-step flowchart for each treatment modality, providing a clear guide for clinical application.

Indexed as

Blood PlateletsWound HealingGuided Tissue Regeneration, PeriodontalHumansPlatelet-Rich Plasmaalveolar ridge preservationAPCARPautogenous platelet concentratesGBRGTRguided bone regenerationguided tissue regenerationintra‐bony defectsmedication‐related osteonecrosis of the jaw bonesMRONJplastic periodontal surgerysinus floor elevation (lateral window techniquetranscrestal technique)

Identifiers

PMID39258791
PMCPMC11808457

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.