Evidence mapPaperPMID 39263480Full record

ArticleCardiovascular diagnosis and therapy2024

Association of serum cystatin C level and major adverse cardiovascular events in patients with percutaneous coronary intervention.

Zhibin Xiao, Aoge Riletu, Xiaoyu Yan, Qi Meng, Weiru Zhang, Na Zhang, Chi Ma, Xin Guo, Jiatong Han, Huijuan Nie and 5 more

Abstract read
In one paragraph

Article in Cardiovascular diagnosis and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Zhibin Xiao *Department of Clinical Pharmacy, College of Pharmacy, Inner Mongolia Medical University, Hohhot, China.
Aoge Riletu *Department of Pharmacy, Inner Mongolian International Mongolian Hospital, Hohhot, China.
Xiaoyu YanDepartment of Clinical Pharmacy, College of Pharmacy, Inner Mongolia Medical University, Hohhot, China.
Qi MengDepartment of Clinical Pharmacy, College of Pharmacy, Inner Mongolia Medical University, Hohhot, China.
Weiru ZhangDepartment of Clinical Pharmacy, College of Pharmacy, Inner Mongolia Medical University, Hohhot, China.
Na ZhangDepartment of Clinical Pharmacy, College of Pharmacy, Inner Mongolia Medical University, Hohhot, China.
Chi MaDepartment of Clinical Pharmacy, College of Pharmacy, Inner Mongolia Medical University, Hohhot, China.
Xin GuoDepartment of Clinical Pharmacy, College of Pharmacy, Inner Mongolia Medical University, Hohhot, China.
Jiatong HanDepartment of Clinical Pharmacy, College of Pharmacy, Inner Mongolia Medical University, Hohhot, China.
Huijuan NieDepartment of Cardiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Hui DengDepartment of Neurology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Jing LiuDepartment of Pharmacy, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Jianping ChenCollege of Pharmacy, Inner Mongolia Medical University, Hohhot, China.
Yu DongDepartment of Natural Medicinal Chemistry, College of Pharmacy, Inner Mongolia Medical University, Hohhot, China.
Tianlong LiuDepartment of Pharmacy, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recurrent acute myocardial infarction requiring unplanned percutaneous coronary intervention (PCI) is one of the major adverse cardiovascular events (MACEs) in patients with acute coronary syndrome (ACS) after PCI. There is a continuing controversy about the association between serum cystatin C, a biomarker for the evaluation of renal function, and the prognosis of ACS patients following PCI. The retrospective study evaluated the association between serum cystatin C level and MACE in ACS patients after PCI. Methods: Data were retrieved for 330 patients with ACS for primary PCI in a single center. Serum cystatin C levels were measured before PCI. All patients underwent regular follow-ups after PCI, and the studied endpoint was MACE, defined as the need for a repeat revascularization in the heart. The predictive value of serum cystatin C for MACE was analyzed using univariate and multivariate analysis. Restricted cubic spline (RCS) analysis was applied to evaluate the dose-response relationship between serum cystatin C level and MACE in ACS patients following PCI. Results: After a median follow-up of 63 months (range, 1-148 months), 121 of the 330 patients experienced MACE. Compared to patients who did not have MACE, patients who had MACE showed a significant decrease in serum cystatin C levels (0.99±0.32 Conclusions: These results indicated an association between serum cystatin C level and post-PCI MACE in ACS patients.

Indexed as

acute coronary syndrome (ACS)Cystatin Cmajor adverse cardiovascular events (MACEs)percutaneous coronary intervention (PCI)U-shaped dose-response relationship

Identifiers

PMID39263480
PMCPMC11384458

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.