Evidence mapPaperPMID 39264188Full record

ArticleAntimicrobial agents and chemotherapy2024

Anti-echinococcal effect of metformin in advanced experimental cystic echinococcosis: reprogrammed intermediary carbon metabolism in the parasite.

Julia A Loos, Perla S Negro, Hugo H Ortega, Facundo J Salinas, Martín Arán, Leonardo Pellizza, Graciela L Salerno, Andrea C Cumino

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julia A LoosIIPROSAM, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata (UNMdP), Mar del Plata, Argentina.ORCID 0000-0002-1407-9114
Perla S NegroParasitología y Enfermedades Parasitarias, Facultad de Ciencias Veterinarias, Universidad Nacional de Rosario, Casilda, Santa Fe, Argentina.
Hugo H OrtegaCentro de Medicina Comparada, ICiVet-Litoral, Universidad Nacional del Litoral-CONICET, Esperanza, Santa Fe, Argentina.
Facundo J SalinasCentro de Medicina Comparada, ICiVet-Litoral, Universidad Nacional del Litoral-CONICET, Esperanza, Santa Fe, Argentina.
Martín AránFundación Instituto Leloir e Instituto de Investigaciones Bioquímicas de Buenos Aires (IIBBA)-CONICET, Buenos Aires, Argentina.
Leonardo PellizzaFundación Instituto Leloir e Instituto de Investigaciones Bioquímicas de Buenos Aires (IIBBA)-CONICET, Buenos Aires, Argentina.
Graciela L SalernoFundación Para Investigaciones Biológicas Aplicadas (FIBA), Mar del Plata, Argentina.ORCID 0000-0001-9177-4199
Andrea C CuminoIIPROSAM, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata (UNMdP), Mar del Plata, Argentina.ORCID 0000-0002-0225-6363

Funding

Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) PIP 2021 N°2473MINCyT | Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT) PICT 2021 N°618Universidad Nacional de Mar del Plata (UNMdP) EXA1164/24
6 · The paper itself

Abstract

Metformin, a safe biguanide derivative with antiproliferative properties, has shown antiparasitic efficacy against the

Indexed as

EchinococcosisMetforminAnimalsCarbonEchinococcus granulosusFemaleGlucoseLarvaMiceCarbonGlucoseMetformincarbon metabolismcystic echinococcosismetformin

Identifiers

PMID39264188
PMCPMC11459915

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.