Evidence map›Paper›PMID 39264374›Full record

ArticleClinical rheumatology2024

Application of superb microvascular imaging technology in clinical disease activity of rheumatoid arthritis.

Yiwen Ou, Jiayu Wu, Yufei Zhu, Xiangjun Qi, Yabing Lou, Guanghui Liu, Jie Jia

Abstract read
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In one paragraph

Article in Clinical rheumatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yiwen OuThe First Clinical Medical School of Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.ORCID http://orcid.org/0009-0003-7551-1083
Jiayu WuThe First Clinical Medical School of Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.ORCID http://orcid.org/0009-0001-3288-8441
Yufei ZhuThe First Clinical Medical School of Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.ORCID http://orcid.org/0009-0004-3110-8038
Xiangjun QiThe First Clinical Medical School of Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Yabing LouBeijing Rehabilitation Hospital, Capital Medical University Gongliao Road, Shijingshan District, Beijing, 100144, China.
Guanghui LiuDepartment of Ultrasound, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, 100102, China.
Jie JiaDepartment of Ultrasound, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 16, Airport Road, Baiyun District, Guangzhou, 510405, Guangdong, China. jiajie110110@126.com.ORCID http://orcid.org/0000-0002-7752-6292

Funding

National Traditional Chinese Medicine Inheritance and Innovation Center Special Research Project in 2023(2023QN16) 2023QN16
6 · The paper itself

Abstract

objectivesDetection of synovitis is essential for assessing the activity and predicting the prognosis of rheumatoid arthritis (RA). The aim of this study was to investigate the diagnostic performance of superb microvascular imaging (SMI) in RA patients with high, moderate, and low activity.

methodsOne hundred four patients with active RA were selected from the hospital between May 2022 and August 2023. The study observed the correlation between bone erosion of the carpal joint, joint cavity effusion, thickness of synovial hyperplasia of the carpal joint, positivity rate of synovial blood vessels, and their semiquantitative scores with the clinical disease activity of RA using SMI examination.

resultsThe detection of synovial hyperplasia thickness and joint effusion in the high-activity group was higher than that in the low-activity group, and the difference was statistically significant (P < 0.05). The quantitative SMI test demonstrated that the synovial blood flow grading and semiquantitative grade increased gradually with activity level (P<0.05). During the high, moderate, and low-activity groups, the vascular index (VI) value of the hyperplastic synovial membrane decreased gradually, showing statistical significance both between and within the groups (P<0.05).

conclusionSMI technology exhibited high sensitivity and accuracy in assessing disease activity in RA. It holds significant clinical application value as a reliable auxiliary tool for assessing disease activity in RA and treatment. Key Points • Super micro-vascular imaging (SMI) demonstrated higher detection rates of microvessels in RA patients with high disease activity compared to those with low activity, showing statistical significance. • The quantitative SMI test revealed a clear correlation between synovial blood flow grading and disease activity levels in RA patients, highlighting the potential of SMI as a valuable tool for disease activity and treatment of rheumatoid arthritis.

Indexed as

Arthritis, RheumatoidMicrovesselsSeverity of Illness IndexSynovial MembraneAdultAgedFemaleHumansMaleMiddle AgedSensitivity and SpecificitySynovitisRheumatoid arthritisSuperb microvascular imagingSynovial vessels

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.