Evidence mapPaperPMID 39267922Full record

ReviewCancer drug resistance (Alhambra, Calif.)2024

The role of circRNAs and miRNAs in drug resistance and targeted therapy responses in breast cancer.

Meilan Zhang, Zhaokuan Zheng, Shouliang Wang, Ruihan Liu, Mengli Zhang, Zhiyun Guo, Hao Wang, Weige Tan

Abstract readReview
In one paragraph

Review in Cancer drug resistance (Alhambra, Calif.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Research (Washington, D.C.) · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Non-Coding RNAs in Breast Cancer: Diagnostic and Therapeutic Implications.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Meilan ZhangThe Affiliated Panyu Central Hospital of Guangzhou Medical University, Guangzhou 511400, Guangdong, China.
Zhaokuan ZhengDepartment of Orthopedics, Affiliated Huadu Hospital, Southern Medical University (People's Hospital of HuaduDistrict), Guangzhou 510810, Guangdong, China.
Shouliang WangDepartment of Breast Surgery, the First Affiliated Hospital, Guangzhou Medical University, Guangzhou 510120, Guangdong, China.
Ruihan LiuDepartment of Breast Surgery, the First Affiliated Hospital, Guangzhou Medical University, Guangzhou 510120, Guangdong, China.
Mengli ZhangDepartment of Breast Surgery, the First Affiliated Hospital, Guangzhou Medical University, Guangzhou 510120, Guangdong, China.
Zhiyun GuoThe Affiliated Panyu Central Hospital of Guangzhou Medical University, Guangzhou 511400, Guangdong, China.
Hao WangThe Affiliated Panyu Central Hospital of Guangzhou Medical University, Guangzhou 511400, Guangdong, China.
Weige TanDepartment of Breast Surgery, the First Affiliated Hospital, Guangzhou Medical University, Guangzhou 510120, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are small non-coding RNAs comprising 19-24 nucleotides that indirectly control gene expression. In contrast to other non-coding RNAs (ncRNAs), circular RNAs (circRNAs) are defined by their covalently closed loops, forming covalent bonds between the 3' and 5' ends. circRNAs regulate gene expression by interacting with miRNAs at transcriptional or post-transcriptional levels. Accordingly, circRNAs and miRNAs control many biological events related to cancer, including cell proliferation, metabolism, cell cycle, and apoptosis. Both circRNAs and miRNAs are involved in the pathogenesis of diseases, such as breast cancer. This review focuses on the latest discoveries on dysregulated circRNAs and miRNAs related to breast cancer, highlighting their potential as biomarkers for clinical diagnosis, prognosis, and chemotherapy response.

Indexed as

breast cancercircRNAsclinical valuesmiRNAs

Identifiers

PMID39267922
PMCPMC11391347

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.