Evidence map›Paper›PMID 39269458›Full record

ArticleLung2024

The Effects of Diabetes on Gas Transfer Capacity, Lung Volumes, Muscle Strength, and Cardio-pulmonary Responses During Exercise.

Eldar Priel, Emir Ali, Danica Brister, Nermin Diab, Andy Freitag, Paul M O'Byrne, Hertzel Gerstein, Kieran J Killian, Imran Satia

Abstract read
PubMed Publisher
In one paragraph

Article in Lung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eldar Priel *Division of Respirology, Department of Medicine, McMaster University, Hamilton, Canada. priele@mcmaster.ca.
Emir Ali *Division of Respirology, Department of Medicine, McMaster University, Hamilton, Canada.
Danica BristerDivision of Respirology, Department of Medicine, McMaster University, Hamilton, Canada.
Nermin DiabDivision of Respirology, Department of Medicine, McMaster University, Hamilton, Canada.
Andy FreitagDivision of Respirology, Department of Medicine, McMaster University, Hamilton, Canada.
Paul M O'ByrneDivision of Respirology, Department of Medicine, McMaster University, Hamilton, Canada.
Hertzel GersteinDivision of Respirology, Department of Medicine, McMaster University, Hamilton, Canada.
Kieran J KillianDivision of Respirology, Department of Medicine, McMaster University, Hamilton, Canada.
Imran SatiaDivision of Respirology, Department of Medicine, McMaster University, Hamilton, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes is a risk factor for the development of vascular disease, chronic kidney disease, retinopathy, and neuropathy. Diabetes is a co-morbid condition commonly present in patients with respiratory disorders but the extent to which it influences ventilatory capacity, gas exchange, and functional capacity is not well known. Research question Does the presence of diabetes contribute to impairment in spirometry, gas transfer, and exercise capacity?

methodsRetrospective analysis of all subjects who performed incremental cardio-pulmonary exercise testing (CPET) between 1988 and 2012 at McMaster University Medical Centre. The impact of diabetes on physiological outcomes and maximum power output (MPO) was assessed using stepwise multiple additive linear regression models including age, height, weight, sex, muscle strength, and previous myocardial infarct as co-variates, and was also stratified based on BMI categories.

results40,776 subjects were included in the analysis; 1938 (5%, 66% male) had diabetes. Diabetics were older (59 vs. 53 years), heavier (88.3 vs.78.0 kg), and had a higher BMI (31 vs. 27 kg/m

conclusionThe presence of diabetes is independently associated with weaker muscles, lower ventilatory and gas transfer capacity and translates to a lower exercise capacity. These differences are independent of age, height, weight, sex, and previous MI.

Indexed as

Exercise TestExercise ToleranceLungMuscle StrengthPulmonary Gas ExchangeAdultAgedBody Mass IndexDiabetes MellitusExerciseFemaleForced Expiratory VolumeHumansLinear ModelsLung Volume MeasurementsMaleCardio-pulmonary exercise testingDiabetesInsulinRespiratory physiologySpirometry

Identifiers

PMID39269458

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.