Evidence map›Paper›PMID 39269582›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2024

The association of the comorbidity status of metabolic syndrome and cognitive dysfunction with health-related quality of life.

Yi-Hsuan Lin, Hsiao-Ting Chang, Yen-Feng Wang, Jong-Ling Fuh, Shuu-Jiun Wang, Harn-Shen Chen, Sih-Rong Li, Ming-Hwai Lin, Tzeng-Ji Chen, Shinn-Jang Hwang

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Yi-Hsuan LinDepartment of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan.
Hsiao-Ting ChangSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan. htchang.tw@gmail.com.ORCID http://orcid.org/0000-0003-0421-8499
Yen-Feng WangSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Jong-Ling FuhSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Shuu-Jiun WangSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Harn-Shen ChenSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Sih-Rong LiDepartment of Family Medicine, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Rd., Beitou Dist, Taipei City, 11217, Taiwan.
Ming-Hwai LinSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Tzeng-Ji ChenSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Shinn-Jang HwangSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.

Funding

Taipei Veterans General Hospital V109E-005-4, V110E-005-4, V111E-006-4, V112E-004-4
6 · The paper itself

Abstract

purposeBoth metabolic syndrome (MetS) and cognitive dysfunction impair health-related quality of life (HRQOL). This study aims to determine whether individuals experiencing both MetS and cognitive dysfunction have lower HRQOL.

methodsThis cross-sectional study enrolled 567 participants who attended outpatient clinics at a medical center in northern Taiwan. MetS was diagnosed according to the modified criteria for the Asian population. Cognitive function was categorized as normal, mild cognitive dysfunction, and advanced cognitive dysfunction according to the score of the Montreal Cognitive Assessment, Taiwanese version. HRQOL was assessed using the SF-36v2® Health Survey (SF-36v2). The associations of the comorbidity status of MetS and cognitive dysfunction with HRQOL were analyzed using linear regression models, adjusting for age, sex, marital status, education level, income groups, and activities of daily living.

resultsOut of 567 participants, 33 (5.8%) had MetS with mild cognitive dysfunction, and 34 (6.0%) had MetS with advanced cognitive dysfunction. Participants with both MetS and advanced cognitive dysfunction exhibited the lowest scores in the physical component summary and almost all scales of HRQOL. MetS exacerbated the inverse association between mild cognitive dysfunction and the mental component summary. For those with MetS, the scores on scales of role physical, bodily pain, vitality, and social functioning worsened as cognitive function deteriorated (all P

conclusionAs the severity of comorbidity between MetS and cognitive dysfunction varies, patients exhibited poorer performance in different aspects of HRQOL. Future research is needed to find solutions to improve HRQOL for patients with both MetS and cognitive dysfunction.

Indexed as

Cognitive DysfunctionComorbidityMetabolic SyndromeQuality of LifeActivities of Daily LivingAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedSurveys and QuestionnairesTaiwanCognitive dysfunctionHealth-related quality of lifeMetabolic syndromeSF-36 Health SurveyTaiwan

Identifiers

PMID39269582

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.