ArticleJournal of nephrology2024
Physical activity and exercise in chronic kidney disease: consensus statements from the Physical Exercise Working Group of the Italian Society of Nephrology.
Article in Journal of nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07483697 (Multimodal Intervention and Its Association With Reduced Dysbiosis and Inflammation in Early Chronic Kidney Disease in Young People), which is not on this map. Cited by 64 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Multimodal Intervention and Its Association With Reduced Dysbiosis and Inflammation in Early Chronic Kidney Disease in Young People: a Prospective Study
Who cites it
64 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Comparative efficacy of different modes of exercise on inflammatory markers in patients with chronic kidney disease: a systematic review with pairwise and network meta-analyses.Scientific reports · 2026Pooled it
- Effects of exercise training on frailty, cardiorespiratory fitness, and lower limb function in non-dialysis chronic kidney disease: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Internet-based remote exercise interventions for maintenance hemodialysis patients: a systematic review of the evidence.BMC nephrology · 2025Pooled it
- Suicide risk in patients undergoing hemodialysis: a systematic review and meta-analysis of prevalence.Renal failure · 2025Pooled it
- Physical activity interventions in adult kidney transplant recipients: an updated systematic review and meta-analysis of randomized controlled trials.Renal failure · 2025Pooled it
- Properties of Measurements of Patient-Reported Outcome Measures Physical Activity Assessment in Chronic Kidney Disease: A Systematic Review.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025Pooled it
- Prescribing Physical Activity and Exercise for People with CKD: A Practical Guide by the Global Renal Exercise Network.Clinical journal of the American Society of Nephrology : CJASN · 2025Guideline
- Effects of exercise dose based on the ACSM recommendations on depression in hemodialysis patients: a systematic review and meta-analysis of randomized controlled trials.Frontiers in physiology · 2024Pooled it
- Does exercise enhance the benefits of nutritional support on the biochemical markers of nutrition, anthropometry, and body composition in hemodialysis patients? A systematic review.Frontiers in nutrition · 2024Pooled it
- Is Adapted Physical Exercise an Innovative Adjuvant Approach to Combine with Low-Protein Diet in Chronic Kidney Disease?Nutrients · 2026Trial
- The Combined Use of Hydroxymethylbutyrate and Branched-Chain Amino Acids to Counteract Uremic Sarcopenia.Nutrients · 2026Trial
- Effects of electrical muscle stimulation during hemodialysis in older patients with frailty: a crossover randomized controlled trial.Journal of nephrology · 2025Trial
- The impact of intradialytic elastic band exercise on physical and cognitive abilities in patients on maintenance hemodialysis: a randomized controlled trial.Renal failure · 2025Trial
- Comparison of the effect of aerobic and resistance training on fatigue, quality of life and biochemical factors in hemodialysis patients.Scientific reports · 2025Trial
- A structured, home-based exercise programme in kidney transplant recipients (ECSERT): A randomised controlled feasibility study.PloS one · 2025Trial
- Physical function, exercise, and clinical outcomes in peritoneal dialysis: a narrative review.International journal of nursing studies advances · 2026Review
- Exercise rehabilitation in frail elderly patients on maintenance hemodialysis: a best evidence summary.International urology and nephrology · 2026Review
- Health-related quality of life for patients on hemodialysis in Saudi Arabia: A cross-sectional study.Medicine · 2026Article
- Associations of exercise habits with physical function and emergency dialysis start in patients with end-stage renal disease before dialysis initiation.Clinical and experimental nephrology · 2026Article
- Blood Flow Restriction Training in Hemodialysis Patients: Clinical Benefits, Challenges, and Future Perspectives.Hemodialysis international. International Symposium on Home Hemodialysis · 2026Review
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Italian Society of Nephrology has tasked its Working Group on Physical Exercise with developing a consensus statement document on physical activity and exercise in patients with chronic kidney disease (CKD). This paper consists of 16 points that were discussed, and approved using the mini-Delphi method by 15 members of the working group. Each statement is based on a comprehensive review of the literature, clinical experience, and expert opinions. Overall, the statements affirm that regular physical activity and exercise training offer numerous benefits to CKD patients, including improved physical function, enhanced cardiometabolic and neuromuscular function, cognitive benefits, and an overall improvement in quality of life. Furthermore, exercise may provide nephroprotection and reduce mortality. These advantages are observed across all CKD stages, whether on conservative therapy or kidney replacement therapy (hemodialysis or peritoneal dialysis), and in kidney transplant recipients. Moreover, when physical activity and exercise training are implemented with appropriate precautions, they are safe in CKD patients. Gradual physical activity and customized exercise programs should be tailored to the patient's exercise tolerance, potentially enhancing compliance. Clinicians are encouraged to use a series of questionnaires and tests to assess the patient's level of physical activity and performance. However, exercise and physical activity are poorly implemented in clinical practice due to many barriers related to patients and healthcare staff. Overcoming these barriers requires the proactive role of the nephrologists, who should actively incorporate exercise training and promote physical activity within routine care plans. Adopting a multidisciplinary team approach, which includes nephrologists, nurses, exercise professionals, and dietitians, is crucial for providing comprehensive rehabilitation for CKD patients. Integrating new technologies and remote check ups could further enhance the effectiveness of these interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.