Evidence map›Paper›PMID 39270515›Full record

ReviewAutonomic neuroscience : basic & clinical2024

The role of peripheral venous distension reflex in regulating hemodynamics: mini review.

Takuto Hamaoka, Lawrence I Sinoway, Jian Cui

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Autonomic neuroscience : basic & clinical, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The effects of limb suction during arterial occlusion on arterial baroreflex in humans.American journal of physiology. Heart and circulatory physiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Takuto HamaokaPenn State Heart and Vascular Institute, Pennsylvania State University College of Medicine, Hershey, PA 17033, United States of America.
Lawrence I SinowayPenn State Heart and Vascular Institute, Pennsylvania State University College of Medicine, Hershey, PA 17033, United States of America.
Jian CuiPenn State Heart and Vascular Institute, Pennsylvania State University College of Medicine, Hershey, PA 17033, United States of America. Electronic address: jcui@pennstatehealth.psu.edu.

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
The Human Cardiovascular Control: The Role of Limb VeinsR01HL144781 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI CUI, JIAN, SINOWAY, LAWRENCE I · 2019 to 2023
$2.7M
NCATS NIH HHS UL1 TR002014NHLBI NIH HHS R01 HL144781
6 · The paper itself

Abstract

Significant volume is pooled in veins in humans and the amount is dramatically altered by various physiological stresses and diseases. Several animal and human studies demonstrated that limb venous distension evoked significant increases in blood pressure and sympathetic nerve activity (venous distension reflex, VDR). VDR has attracted much attention because of its potential to explain the still unknown mechanism of autonomic dysfunction in several diseases, which would lead to a new treatment approach. This mini review discusses accumulated evidence of VDR at this point and what should be investigated in the future to apply the current understanding of VDR in clinical practice.

Indexed as

HemodynamicsReflexVeinsAnimalsHumansSympathetic Nervous SystemAutonomic nerve functionBlood pressureMuscle sympathetic nerve activityPeripheral veinVenous distension reflex

Identifiers

PMID39270515
PMCPMC11631646

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.