ArticleNature cardiovascular research2024
Tissue-resident memory T cells in epicardial adipose tissue comprise transcriptionally distinct subsets that are modulated in atrial fibrillation.
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Article in Nature cardiovascular research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33citing papers in PubMed
–field-weighted citation impact
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed.
- Cytomegalovirus Latency Fuels Inflammation Following Myocardial Infarction.Circulation research · 2026Article
- Reconstructing AF-associated atrial fibrosis: Patient-specific iPSC models, fit-for-purpose atrial microphysiological systems, and nanomedicine.Materials today. Bio · 2026Review
- Reversing the pipeline: a 'human-first' multi-omics approach to cardiovascular discovery.Experimental & molecular medicine · 2026Review
- The Heart's Hidden Influencer: Epicardial Adipose Tissue in the Pathogenesis of Heart Failure.Cardiology discovery · 2026Review
- Myocardial Immune Niches in Homeostasis and Inflammation.Immunological reviews · 2026Review
- Metabolic Reprogramming-Driven Cardiovascular Immune Damage: From Glyco-Lipotoxicity and Epigenetic Memory to Multidimensional Cross-Organ Communication Networks.International journal of molecular sciences · 2026Review
- T Cell Receptor Repertoires Across the Continuum of Vascular, Myocardial, and Age-Related Diseases.Immunological reviews · 2026Review
- Tissue-resident memory T cells in organ transplantation: implications for immune homeostasis and graft outcomes.Inflammation and regeneration · 2026Review
- Epicardial Adipose Tissue as a Cardiometabolic Target in Atrial Fibrillation: Implications for Ablation Strategies and Emerging Metabolic Therapies.Medical sciences (Basel, Switzerland) · 2026Review
- Inflammation and Resolution in Obesity-Related Cardiovascular Disease.International journal of molecular sciences · 2026Review
- Metabolic and Inflammatory Mechanisms Driving Atrial Fibrillation.Annual review of pharmacology and toxicology · 2026Review
- Association between the triglyceride-high-density lipoprotein-glucose-body index and atrial fibrillation: a retrospective case-control study.Frontiers in nutrition · 2026Article
- Heart failure and its progression is associated with changed lymphocyte profile in epicardial adipose tissue.Frontiers in immunology · 2026Article
- Defective efferocytosis links autonomic dysfunction and atrial fibrillation: multi-omics integration andFrontiers in immunology · 2026Article
- The metabolic-inflammatory axis in chronic heart failure: integrating the NLR and TyG index for recent-onset atrial fibrillation prediction via machine learning and mediation analysis.Frontiers in endocrinology · 2026Article
- Cxcl9 as a Marker of Adipose Tissue Changes Caused by Bariatric Surgery and Psoriasis.Clinical, cosmetic and investigational dermatology · 2026Article
- From skin to heart: a state-of-the-art perspective on psoriasis-driven cardiovascular comorbidities.Frontiers in immunology · 2026Review
- Integrating Bioprinting and Increased Throughput: Next-Generation Models for Cardiac Research.International journal of molecular sciences · 2025Review
- Heart-guarding or heart-harming? The dual role of epicardial adipose tissue in cardiovascular health and disease.International journal of obesity (2005) · 2025Review
- Resolution Pharmacology: State-of-the-art and therapeutic landscape.Pharmacological reviews · 2025Review
Corrections and comments
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Authors and funding
20 authors.
Vishal VyasWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Balraj SandharWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0001-7569-0163
Jack M KeaneWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID http://orcid.org/0009-0002-8248-7563
Elizabeth G WoodWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Hazel BlytheWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0002-7824-4019
Aled JonesWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0002-6718-0646
Eriomina ShahajWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0001-5428-0405
Silvia FantiWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0003-2505-7102
Jack WilliamsWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Nasrine MeticCancer Research UK, Barts Centre, Queen Mary University of London, London, UK.ORCID http://orcid.org/0009-0007-1723-5390
Mirjana EfremovaCancer Research UK, Barts Centre, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0002-8107-9974
Han Leng NgDepartment of Immunology and Inflammation, Centre for Haematology, Faculty of Medicine, Imperial College London, London, UK.ORCID http://orcid.org/0000-0001-7316-2842
Gayathri NageswaranUCL Division of Infection and Immunity, University College London, London, UK.
Suzanne ByrneUCL Division of Infection and Immunity, University College London, London, UK.
Niklas FeldhahnDepartment of Immunology and Inflammation, Centre for Haematology, Faculty of Medicine, Imperial College London, London, UK.
Federica Marelli-BergWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0001-8747-5823
Benny ChainUCL Division of Infection and Immunity, University College London, London, UK.
Andrew TinkerWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0001-7703-4151
Malcolm C FinlayWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
M Paula LonghiWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. m.longhi@qmul.ac.uk.ORCID http://orcid.org/0000-0003-1854-4594
Funding
LIFESTYLE AND CHRONIC DISEASE IN COLLEGE ALUMNIR01HL034174 · NHLBI · STANFORD UNIVERSITY · PI PAFFENBARGER, RALPH S · 1985 to 1998
–British Heart Foundation (BHF) AA/18/5/34222British Heart Foundation (BHF) FS/13/49/30421British Heart Foundation (BHF) FS/4yPhD/F/22/34174BBritish Heart Foundation (BHF) PG/16/79/32419RCUK | MRC | Medical Research Foundation MR/T008059/1
Abstract
Atrial fibrillation (AF) is the most common sustained arrhythmia and carries an increased risk of stroke and heart failure. Here we investigated how the immune infiltrate of human epicardial adipose tissue (EAT), which directly overlies the myocardium, contributes to AF. Flow cytometry analysis revealed an enrichment of tissue-resident memory T (T
Indexed as
Adipose TissueAtrial FibrillationMemory T CellsPericardiumAgedApoptosisCalcium SignalingCase-Control StudiesCD8-Positive T-LymphocytesEpicardial Adipose TissueFemaleFibrosisGene Expression ProfilingHeart AtriaHumansImmunologic Memory
Identifiers
What Socratic holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.