Evidence map›Paper›PMID 39273564›Full record

ArticleInternational journal of molecular sciences2024

Antonio Tejera-Muñoz, Marcelino Cortés, Alianet Rodriguez-Rodriguez, Lucia Tejedor-Santamaria, Vanessa Marchant, Sandra Rayego-Mateos, Maria José Gimeno-Longas, Andrew Leask, Tri Q Nguyen, María Martín and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Antonio Tejera-MuñozResearch Unit, Complejo Hospitalario La Mancha Centro, 13600 Alcázar de San Juan, Spain.ORCID 0000-0002-7954-5753
Marcelino CortésCardiology Department, Hospital Universitario Fundación Jiménez Díaz, 28040 Madrid, Spain.ORCID 0000-0002-2304-8547
Alianet Rodriguez-RodriguezDepartamento de Biología de Sistemas, Universidad de Alcalá, 28871 Alcalá de Henares, Spain.
Lucia Tejedor-SantamariaCellular and Molecular Biology in Renal and Vascular Pathology Laboratory, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz, Universidad Autónoma de Madrid, 28040 Madrid, Spain.ORCID 0000-0003-4295-7284
Vanessa MarchantCellular and Molecular Biology in Renal and Vascular Pathology Laboratory, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz, Universidad Autónoma de Madrid, 28040 Madrid, Spain.ORCID 0000-0002-2767-0229
Sandra Rayego-MateosCellular and Molecular Biology in Renal and Vascular Pathology Laboratory, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz, Universidad Autónoma de Madrid, 28040 Madrid, Spain.
Maria José Gimeno-LongasDepartment of Cell Biology, School of Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0002-2086-9534
Andrew LeaskCollege of Dentistry, University of Saskatchewan, 105 Wiggins Road, Saskatoon, SK S7N 5E4, Canada.ORCID 0000-0003-2832-283X
Tri Q NguyenDepartment of Pathology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.ORCID 0000-0001-6475-0706
María MartínCardiology Department, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Jose TuñónCardiology Department, Hospital Universitario Fundación Jiménez Díaz, 28040 Madrid, Spain.ORCID 0000-0002-1373-0999
Isabel RodríguezCardiac Pathology Research Group, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), 33011 Oviedo, Spain.ORCID 0000-0001-7213-1411
Marta Ruiz-OrtegaCellular and Molecular Biology in Renal and Vascular Pathology Laboratory, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz, Universidad Autónoma de Madrid, 28040 Madrid, Spain.ORCID 0000-0002-1495-6535
Raul R Rodrigues-DíezRICORS2040, Instituto de Salud Carlos III, 28040 Madrid, Spain.

Funding

Instituto de Salud Carlos III (ISCIII) and Fondos FEDER European Union INNOREN P2022/BMD-7221Instituto de Salud Carlos III (ISCIII) and Fondos FEDER European Union PI20/00140 and PI23/00394Instituto de Salud Carlos III (ISCIII) and Fondos FEDER European Union RICORS2040; RD21/0005/0002Miguel Servet ISCIII program CP23/00025Sociedad Española de Arteriosclerosis to Raul Rodrigues-DiezSociedad Española de Cardiología to Marta Ruiz-Ortega
6 · The paper itself

Abstract

Cellular Communication Network Factor 2 (CCN2) is a matricellular protein implicated in cell communication and microenvironmental signaling. Overexpression of CCN2 has been documented in various cardiovascular pathologies, wherein it may exert either deleterious or protective effects depending on the pathological context, thereby suggesting that its role in the cardiovascular system is not yet fully elucidated. In this study, we aimed to investigate the effects of

Indexed as

Connective Tissue Growth FactorDoxorubicinFibrosisMice, KnockoutOxidative StressAnimalsCardiotoxicityGene DeletionMaleMiceMice, Inbred C57BLMyocardiumCCN2 protein, mouseConnective Tissue Growth FactorDoxorubicincardiac dysfunctionCCN2doxorubicinfibrosisoxidative stress

Identifiers

PMID39273564
PMCPMC11394698

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.