Evidence mapPaperPMID 39273680Full record

ReviewInternational journal of molecular sciences2024

Oral Health and Nutraceutical Agents.

Mariantonietta Leo, Floriana D'Angeli, Carlo Genovese, Antonella Spila, Chiara Miele, Dania Ramadan, Patrizia Ferroni, Fiorella Guadagni

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mariantonietta LeoDepartment of Promotion of Human Sciences and Quality of Life, San Raffaele Roma Open University, 00166 Rome, Italy.ORCID 0000-0001-9588-7668
Floriana D'AngeliDepartment of Promotion of Human Sciences and Quality of Life, San Raffaele Roma Open University, 00166 Rome, Italy.ORCID 0000-0002-1831-0432
Carlo GenoveseDepartment of Medicine and Surgery, "Kore" University of Enna, Contrada Santa Panasia, 94100 Enna, Italy.ORCID 0000-0003-2463-9047
Antonella SpilaDepartment of Promotion of Human Sciences and Quality of Life, San Raffaele Roma Open University, 00166 Rome, Italy.
Chiara MieleDepartment of Promotion of Human Sciences and Quality of Life, San Raffaele Roma Open University, 00166 Rome, Italy.
Dania RamadanDepartment of Promotion of Human Sciences and Quality of Life, San Raffaele Roma Open University, 00166 Rome, Italy.
Patrizia FerroniDepartment of Promotion of Human Sciences and Quality of Life, San Raffaele Roma Open University, 00166 Rome, Italy.ORCID 0000-0002-9877-8712
Fiorella GuadagniDepartment of Promotion of Human Sciences and Quality of Life, San Raffaele Roma Open University, 00166 Rome, Italy.

Funding

European Social Fund PO FESR Sicily 2014-2020 G88I18000710007Ministero della Salute NA
6 · The paper itself

Abstract

Oral health is essential for both overall health and quality of life. The mouth is a window into the body's health, and nutrition can strongly impact the state of general and oral health. A healthy diet involves the synergistic effect of various nutraceutical agents, potentially capable of conferring protective actions against some inflammatory and chronic-degenerative disorders. Nutraceuticals, mostly present in plant-derived products, present multiple potential clinical, preventive, and therapeutic benefits. Accordingly, preclinical and epidemiological studies suggested a protective role for these compounds, but their real preventive and therapeutic effects in humans still await confirmation. Available evidence suggests that plant extracts are more effective than individual constituents because they contain different phytochemicals with multiple pharmacological targets and additive/synergistic effects, maximizing the benefits for oral health. Moreover, nutritional recommendations for oral health should be personalized and aligned with valid suggestions for overall health. This review is aimed to: introduce the basic concepts of nutraceuticals, including their main food sources; examine the logic that supports their relationship with oral health, and summarize and critically discuss clinical trials testing the utility of nutraceuticals in the prevention and treatment of oral diseases.

Indexed as

Dietary SupplementsOral HealthAnimalsHumansPhytochemicalsPlant ExtractsQuality of LifePhytochemicalsPlant Extractsanticancer activityantimicrobial activityantioxidant activitynutraceuticalsoral diseasesoral health

Identifiers

PMID39273680
PMCPMC11395598

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.