Evidence map›Paper›PMID 39275333›Full record

Trial reportNutrients2024

No Difference between the Efficacy of High-Nitrate and Low-Nitrate Vegetable Supplementation on Blood Pressure after 16 Weeks in Individuals with Early-Stage Hypertension: An Exploratory, Double-Blinded, Randomized, Controlled Trial.

Dandan Li, Elena Jovanovski, Andreea Zurbau, John Sievenpiper, Davor Milicic, Ahmed El-Sohemy, Vladimir Vuksan

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dandan LiDepartment of Nutritional Sciences, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.
Elena JovanovskiDepartment of Nutritional Sciences, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.
Andreea ZurbauDepartment of Nutritional Sciences, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.ORCID 0000-0003-2927-3689
John SievenpiperDepartment of Nutritional Sciences, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.
Davor MilicicDepartment of Cardiovascular Diseases, School of Medicine, University of Zagreb, University Hospital Center Zagreb, Kispaticeva 12, 10000 Zagreb, Croatia.
Ahmed El-SohemyDepartment of Nutritional Sciences, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.ORCID 0000-0002-8877-6414
Vladimir VuksanDepartment of Nutritional Sciences, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.ORCID 0000-0001-8541-4058

Funding

CIHR 377787
6 · The paper itself

Abstract

Dietary inorganic nitrate lowers blood pressure (BP) in healthy individuals through improved nitric oxide (NO) bioavailability. However, there is limited evidence examining the long-term effects of dietary nitrate for managing hypertension. We aimed to determine whether the sustained intake of dietary nitrate improved BP and cardiovascular disease (CVD) risk factors in individuals with early-stage hypertension. The Dietary Nitrate (NO

Indexed as

Blood PressureDietary SupplementsHypertensionNitratesVegetablesAdultDouble-Blind MethodFemaleHumansMaleMiddle AgedPulse Wave AnalysisTreatment OutcomeNitratesarterial stiffnessblood pressurecardiovascular disease risk factorsdietary nitrateheart-healthy dietnitric oxidevegetable supplement

Identifiers

PMID39275333
PMCPMC11397180

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.