SynthesisInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society2024
Association between Silva pattern-based classification and endocervical adenocarcinoma: a systematic review and meta-analysis.
Synthesis in International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Review
- Identification of low-risk cases of invasive endocervical adenocarcinoma with Silva pattern-based classification: a systematic review andGynecologic oncology reports · 2025Article
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5 authors.
Funding
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Abstract
objectiveTo determine the relationship between the Silva pattern-based classification system and endocervical adenocarcinoma.
methodsThe PubMed, Embase, Central Cochrane Library, and Web of Science databases were systematically searched for studies that investigated the correlation between the Silva classification system and the oncology prognosis or pathological features of endocervical adenocarcinoma, published in the period from January 2013 to March 2024.
resultsA total of 19 eligible studies including 3122 cases were included in this systematic review and meta-analysis. The combined death rate in the Silva A, Silva B, and Silva C patterns was 0% (95% CI 0.0% to 0.4%), 2.6% (95% CI 0.4% to 5.9%), and 14.0% (95% CI 9.4% to 19.2%), respectively; the combined recurrence rate in the Silva A, Silva B, and Silva C patterns was 0.1% (95% CI 0.0% to 1.2%), 5.1% (95% CI 1.6% to 10.0%), and 19.4% (95% CI 14.7% to 24.4%), respectively; the combined lymphovascular invasion rate in the Silva A, Silva B, and Silva C patterns was 0% (95% CI 0.0% to 0.5%), 21.0% (95% CI 16.9% to 25.4%), and 58.8% (95% CI 50.1% to 67.3%), respectively; and the combined International Federation of Gynecology and Obstetrics (FIGO) I rate in the Silva A, Silva B, and Silva C patterns was 99.3% (95% CI 97.6% to 100%), 93.7% (95% CI 86.4% to 98.7%), and 82.4% (95% CI 74.9% to 88.9%), respectively.
conclusionOur study found that Silva A was negatively correlated with death rate, while Silva C was positively correlated. There was no correlation regarding the death rate for Silva B. Based on these findings, it is suggested that the Silva pattern-based classification system can predict the prognosis of human papillomavirus (HPV)-related endocervical adenocarcinoma and assist in guiding patient treatment.
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