Evidence map›Paper›PMID 39280110›Full record

ArticleMaterials today. Bio2024

Magnetic stirring with iron oxide nanospinners accretes neurotoxic Aβ

Arjun Sabu, Yu Ching Huang, Ramalingam Sharmila, Chih-Yuan Sun, Min-Ying Shen, Hsin-Cheng Chiu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Chicoric acid enhanced brain cholesterol efflux and reduced Aβ pathology via LXR-ABCA1 signaling in Alzheimer's models.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arjun SabuDepartment of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu City, Taiwan.
Yu Ching HuangDepartment of Neurology, Taoyuan General Hospital, Ministry of Health and Welfare, Taiwan.
Ramalingam SharmilaDepartment of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu City, Taiwan.
Chih-Yuan SunDepartment of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu City, Taiwan.
Min-Ying ShenDepartment of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu City, Taiwan.
Hsin-Cheng ChiuDepartment of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu City, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An increasing number of medications have been explored to treat the progressive and irreversible Alzheimer's disease (AD) that stands as the predominant form of dementia among neurodegenerative ailments. However, assertions about toxic side effects of these drugs are a significant hurdle to overcome, calling for drug-free nanotherapeutics. Herein, a new therapeutic strategy devoid of conventional drugs or other cytotoxic species was developed. The constructed superparamagnetic iron oxide nanoparticles (SPIONs) nanospinners can accrete neurotoxic β-amyloid 42 oligomers (oAβ

Indexed as

Alzheimer's diseaseMicroglial cell polarizationNanoscaled stirring treatmentPhagocytic clearanceSuperparamagnetic iron oxide nanoparticlesβ-Amyloid 42 oligomers

Identifiers

PMID39280110
PMCPMC11402446

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.