Evidence map›Paper›PMID 39280806›Full record

ArticleACS materials Au2024

In Vivo Assessment of a Triple Periodic Minimal Surface Based Biomimmetic Gyroid as an Implant Material in a Rabbit Tibia Model.

Pearlin Amaan Khan, Ansheed Raheem, Cheirmadurai Kalirajan, Konda Gokuldoss Prashanth, Geetha Manivasagam

Abstract read
In one paragraph

Article in ACS materials Au, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pearlin Amaan KhanCentre for Biomaterials, Cellular, and Molecular Theranostics, Vellore Institute of Technology, Vellore 632014, India.
Ansheed RaheemCentre for Biomaterials, Cellular, and Molecular Theranostics, Vellore Institute of Technology, Vellore 632014, India.
Cheirmadurai KalirajanCentre for Biomaterials, Cellular, and Molecular Theranostics, Vellore Institute of Technology, Vellore 632014, India.
Konda Gokuldoss PrashanthCentre for Biomaterials, Cellular, and Molecular Theranostics, Vellore Institute of Technology, Vellore 632014, India.ORCID https://orcid.org/0000-0001-5644-2527
Geetha ManivasagamCentre for Biomaterials, Cellular, and Molecular Theranostics, Vellore Institute of Technology, Vellore 632014, India.ORCID https://orcid.org/0000-0003-3326-3176

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biomimetic approaches to implant construction are a rising frontier in implantology. Triple Periodic Minimal Surface (TPMS)-based additively manufactured gyroid structures offer a mean curvature of zero, rendering this structure an ideal porous architecture. Previous studies have demonstrated the ability of these structures to effectively mimic the mechanical cues required for optimal implant construction. The porous nature of gyroid materials enhances bone ingrowth, thereby improving implant stability within the body. This enhancement is attributed to the increased surface area of the gyroid structure, which is approximately 185% higher than that of a dense material of the same form factor. This larger surface area allows for enhanced cellular attachment and nutrient circulation facilitated by the porous channels. This study aims to evaluate the biological performance of a gyroid-based Ti6Al-4V implant material compared to a dense alloy counterpart. Cellular viability was assessed using the lactate dehydrogenase (LDH) assay, which demonstrated that the gyroid surface allowed marginally higher viability than dense material. The

Identifiers

PMID39280806
PMCPMC11393938

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.