Molecular evaluation of early-age plasma adiponectin levels in young obese cases with diabetes mellitus type 1.

Abousree T Ellethy, Mohamed E Hagag

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Article in International journal of health sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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2 authors.

Abousree T EllethyDepartment of Basic Oral Sciences and Dental Education, Biochemistry Division, College of Dentistry, Qassim University, Buraydah, Saudi Arabia.

Mohamed E HagagDepartment of Physiology, College of Medicine, Qassim University, Buraydah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Adiponectin (ADN) is related to insulin resistance and cardiovascular disorders risks. It is negatively controlled in obese cases among diabetes mellitus type 1 (DMT1) patients. The current study evaluates ADN levels in early-aged children 9-12 years old of obese and non-obese cases (DMT1). Methods: A cross-sectional study among children aged 9-11 years old, was conducted during the year 2023 within two groups. First was a diabetic children DMT1 group excluding diabetic cases with complications. Second was a healthy children's control group. Two groups were subdivided into two subgroups, obese and non-obese ( Results: Significantly increased plasma AND levels were detected in DMT1 patients compared to non-diabetic cases ( Conclusion: Plasma ADN levels were significantly reduced in obese subjects' diabetics or non-diabetics. It may refer to insulin resistance or mechanisms that prevent further weight gain by decreasing insulin sensitivity and increasing energy expenditure.

Indexed as

AdiponectinDiabetes mellitus type 1Insulin resistanceObese diabetic children

Identifiers

PMID39282128

PMCPMC11393390

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LicenceCC BY-NC-SA

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.