Evidence map›Paper›PMID 39282315›Full record

ArticlebioRxiv : the preprint server for biology2024

Transfer RNA levels are tuned to support differentiation during Drosophila neurogenesis.

Rhondene Wint, Michael D Cleary

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Rhondene WintDepartment of Molecular and Cell Biology, Quantitative and Systems Biology Graduate Program, University of California, Merced, CA, USA.
Michael D ClearyDepartment of Molecular and Cell Biology, Quantitative and Systems Biology Graduate Program, University of California, Merced, CA, USA.ORCID 0000-0001-9428-8954

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Transfer RNA Dynamics During Neural DifferentiationR21NS121995 · NINDS · UNIVERSITY OF CALIFORNIA, MERCED · PI CLEARY, MICHAEL · 2021 to 2021
$413k
NIH HHS P40 OD018537NINDS NIH HHS R21 NS121995
6 · The paper itself

Abstract

Neural differentiation requires a multifaceted program to alter gene expression along the proliferation to differentiation axis. While critical changes occur at the level of transcription, post-transcriptional mechanisms allow fine-tuning of protein output. We investigated the role of tRNAs in regulating gene expression during neural differentiation by quantifying tRNA abundance in neural progenitor-biased and neuron-biased

Identifiers

PMID39282315
PMCPMC11398488

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.