Evidence map›Paper›PMID 39282473›Full record

ReviewFrontiers in cell and developmental biology2024

Von Willebrand factor and hematogenous cancer metastasis under flow.

Wenxuan Xu, Xi Tan, Morgan L Li, Hanzhi Xu, Jasmine Villegas, Hongxia Fu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cell and developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenxuan Xu *Division of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, WA, United States.
Xi Tan *Division of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, WA, United States.
Morgan L LiDivision of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, WA, United States.
Hanzhi XuDivision of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, WA, United States.
Jasmine VillegasDivision of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, WA, United States.
Hongxia FuDivision of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, WA, United States.

Funding

Mechanisms of interactions between von Willebrand factor and its binding partnersR01HL167688 · NHLBI · UNIVERSITY OF WASHINGTON · PI Hongxia Fu · 2023 to 2026
$2.7M
Unveiling Functional Roles of Apical Surface Interactions Between Opposing Cell LayersR35GM149516 · NIGMS · UNIVERSITY OF WASHINGTON · PI Hongxia Fu · 2023 to 2026
$1.8M
NHLBI NIH HHS R01 HL167688NIGMS NIH HHS R35 GM149516
6 · The paper itself

Abstract

Hematogenous metastasis involves cancer cell migration to different locations from the primary tumor through the blood circulation. Von Willebrand factor (VWF) has been shown to play an important role in tumor cell adhesion to and extravasation from the endothelial cell lining of blood vessel walls during cancer metastasis. VWF may contribute to this process by interacting with tumor cells, endothelial cells, and platelets through various cell membrane receptors, such as platelet glycoprotein (GP)Ibα, P-selectin, α

Indexed as

cancerendothelial cellsflowmetastasisplateletsVon Willebrand factor

Identifiers

PMID39282473
PMCPMC11401050

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.