ReviewCell biochemistry and biophysics2025
The Association between the NLRP3 Inflammasome and Specific Long-Non Coding RNAs (lncRNAs) in Cancer; New Perspective and Summary of Recent Studies.
Review in Cell biochemistry and biophysics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In response to cellular perturbations, a multimeric cytosolic protein complex known as the NLRP3 inflammasome assembles. As a result of this assembly, caspase-1 is activated, which encourages inflammatory cell death (pyroptosis) as well as the maturation and release of the inflammatory cytokines interleukin-1β (IL-1β) and IL-18. Tumor etiology involves dysregulation of NLRP3 inflammasome activation, but because of conflicting results, its significance in the onset and spread of cancer is still up for debate. New research indicates that long-non coding RNAs (lncRNAs) play a crucial part in controlling the activity of the NLRP3 inflammasome in a number of disorders. Non-coding RNAs longer than 200 nucleotides are known as lncRNAs. Cancer development has been connected to its deregulation in the development of illnesses. Growing data suggests that controlling lncRNAs on the NLRP3 inflammasome plays a crucial role in the emergence and progression of cancer-related challenges. Here, we discuss over how lncRNAs control the NLRP3 inflammasome and how it functions in different types of cancer cells, offering new perspectives on creating new cancer treatment strategies in the future.
Indexed as
Identifiers
39285156What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.