Evidence map›Paper›PMID 39285353›Full record

ArticleBMC gastroenterology2024

Association between lipid accumulation products and gallstones: an analysis of the National Health and Nutrition Examination Survey 2017-2020.

Huimin Wang, Xiaojia Feng, Qihui Huang, Xiaowei Zheng

Abstract read
In one paragraph

Article in BMC gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Huimin WangDepartment of Endocrinology, Hefei Hospital Affiliated to Anhui Medical University, Hefei, 230000, China.
Xiaojia FengDepartment of Oncology, The First Affiliated Hospital of Anhui University of Science and Technology, Huainan, 232000, China.
Qihui HuangDepartment of Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230000, China.
Xiaowei ZhengDepartment of Infection, Hospital for Infectious Diseases, Anhui Provincial Hospital, Hefei, 230000, China. sainwell@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe aim of the research was to look into the connection between the occurrence of gallstones in adult US citizens and lipid accumulation products (LAP).

methodsWe conducted a cross-sectional study of 3,582 U.S. adults with relevant indicators collected from the 2017-2020 National Health and Nutrition Examination Survey (NHANES) database. Multifactorial logistic regression was used to investigate the linear relationship between LAP and gallstone incidence, while smoothed curve fitting was used to describe the nonlinear relationship, and subgroup and interaction analyses were used to evaluate the potential differences between groups.

resultsAmong the 3582 participants aged ≥ 20 years included, there was a positive association between LAP and gallstones. Following adjustments for all covariates, the likelihood of getting gallstones rose by 29% for each unit rise in log2-LAP (OR = 1.29, 95% CI: 1.13‒1.49). Compared to those in the lowest tertile, those in the highest LAP tertile had a significantly higher risk of developing gallstones (OR = 1.97, 95% CI: 1.31‒2.95). Subgroup analyses indicated that the association between LAP and gallstones was not affected by the stratification of the variables examined.

conclusionGallstones and LAP exhibited a positive association in our investigation, indicating that LAP may be utilized as a clinical indicator to determine the occurrence of gallstones.

Indexed as

GallstonesLipid Accumulation ProductNutrition SurveysAdultAgedCross-Sectional StudiesFemaleHumansIncidenceLogistic ModelsMaleMiddle AgedRisk FactorsUnited StatesYoung AdultCross-sectional studyGallstonesLipid accumulation productsNHANES

Identifiers

PMID39285353
PMCPMC11406836

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.