Article in Prion, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
6 authors.
Anthony E KincaidDepartment of Pharmacy Sciences, School of Pharmacy and Health Professions, Creighton University, Omaha, NE, USA.ORCID 0000-0002-5700-5887
Nathaniel D DenkersDepartment of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Erin E McNultyDepartment of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Caitlyn N KraftDepartment of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Jason C BartzDepartment of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, NE, USA.ORCID 0000-0003-4081-7886
Candace K MathiasonDepartment of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Funding
Zoonotic potential of CWD and influence of environmental contamination on prion propagationP01AI077774 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI CLAUDIO SOTO · 2008 to 2026
$36.1M
Transmission and Pathogenesis of Chronic Wasting Disease (CWD)R01NS061902 · NINDS · COLORADO STATE UNIVERSITY · PI MATHIASON, CANDACE K. · 2009 to 2022
$5.3M
Detection and Characterization of Blood-borne PrionsR01AI112956 · NIAID · COLORADO STATE UNIVERSITY · PI MATHIASON, CANDACE K. · 2014 to 2024
$4.6M
Chronic Wasting Disease VaccinesR01AI156037 · NIAID · COLORADO STATE UNIVERSITY · PI MATHIASON, CANDACE K. · 2021 to 2025
$3.5M
Mechanisms of prion spread and establishment of infectionR01NS107246 · NINDS · CREIGHTON UNIVERSITY · PI BARTZ, JASON C, KINCAID, ANTHONY E. · 2018 to 2022
Chronic wasting disease (CWD) is a transmissible and fatal prion disease that affects cervids. While both oral and nasal routes of exposure to prions cause disease, the spatial and temporal details of how prions enter the central nervous system (CNS) are unknown. Carotid bodies (CBs) are structures that are exposed to blood-borne prions and are densely innervated by nerves that are directly connected to brainstem nuclei, known to be early sites of prion neuroinvasion. All CBs examined contained mast cells expressing the prion protein which is consistent with these cells playing a role in neuroinvasion following prionemia.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Expression of the cellular prion protein by mast cells in white-tailed deer carotid body, cervical lymph nodes and ganglia. · full record | Socratic