Evidence map›Paper›PMID 39285918›Full record

ArticlePeerJ2024

Identifying transgene insertions in

Paula E Adams, Jennifer L Thies, John M Sutton, Joshua D Millwood, Guy A Caldwell, Kim A Caldwell, Janna L Fierst

Abstract read
In one paragraph

Article in PeerJ, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Transgene Mapping in Animals: What to Choose?International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paula E AdamsDepartment of Biological Sciences, Auburn University, Auburn, AL, United States of America.
Jennifer L ThiesDepartment of Biological Sciences, University of Alabama - Tuscaloosa, Tuscaloosa, AL, United States of America.
John M SuttonDepartment of Biological Sciences, University of Alabama - Tuscaloosa, Tuscaloosa, AL, United States of America.
Joshua D MillwoodDepartment of Biological Sciences, University of Alabama - Tuscaloosa, Tuscaloosa, AL, United States of America.
Guy A CaldwellDepartment of Biological Sciences, University of Alabama - Tuscaloosa, Tuscaloosa, AL, United States of America.
Kim A CaldwellDepartment of Biological Sciences, University of Alabama - Tuscaloosa, Tuscaloosa, AL, United States of America.
Janna L FierstDepartment of Biological Sciences, Florida International University, Miami, FL, United States of America.

Funding

Structural variants and the locus of evolutionR35GM147245 · NIGMS · FLORIDA INTERNATIONAL UNIVERSITY · PI Janna Lynn Fierst · 2022 to 2026
$1.8M
NIGMS NIH HHS R35 GM147245
6 · The paper itself

Abstract

Genetically modified organisms are commonly used in disease research and agriculture but the precise genomic alterations underlying transgenic mutations are often unknown. The position and characteristics of transgenes, including the number of independent insertions, influences the expression of both transgenic and wild-type sequences. We used long-read, Oxford Nanopore Technologies (ONT) to sequence and assemble two transgenic strains of

Indexed as

Animals, Genetically ModifiedCaenorhabditis elegansNanopore SequencingTransgenesalpha-SynucleinAnimalsGenome, HelminthGreen Fluorescent ProteinsHumansMutagenesis, Insertionalalpha-SynucleinGreen Fluorescent ProteinsC. elegansGenome assemblyNeurodegenerationTransgenic lines

Identifiers

PMID39285918
PMCPMC11404476

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.