Evidence map›Paper›PMID 39286229›Full record

ArticleHeliyon2024

A bio-functional cryogel with antioxidant activity for potential application in bone tissue repairing.

Feng Chen, Wenbiao Zheng, Zeyu Yang, Wei Wang, Jiehe Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Feng ChenDepartment of Orthopedics, Taizhou Municipal Hospital, Taizhou, 318000, Zhejiang Province, PR China.
Wenbiao ZhengDepartment of Orthopedics, Taizhou Municipal Hospital, Taizhou, 318000, Zhejiang Province, PR China.
Zeyu YangDepartment of Orthopedics, Taizhou Municipal Hospital, Taizhou, 318000, Zhejiang Province, PR China.
Wei WangDepartment of Tumor Intervention, Taizhou Municipal Hospital, Taizhou, 318000, Zhejiang Province, PR China.
Jiehe HuangDepartment of Orthopedics, Taizhou Municipal Hospital, Taizhou, 318000, Zhejiang Province, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antioxidant and free radical resistance has been a key concern of tissue engineering. In this study, Hydroxyapatite (HAp) with osteogenic activity and Oligomeric Proantho Cyanidins (OPC) with antioxidant activity were chemically grafted to prepare gelatin-based biofunctional aerogel (GHPOS). SEM results confirmed that these aerogels exhibited obvious macroporous structure and could provide a suitable microenvironment for bone cell growth. The addition of HAP-PEI-OPC made it have good antioxidant activity, and the cell results proved that the aerogel prepared in this study had good cytocompatibility and did not produce cytotoxicity. The addition of nanoparticles played an important role in the activity of 3T3-E1. The results showed that these bioactive aerogel scaffolds have potential applications in bone tissue engineering.

Indexed as

AerogelAntioxidant activityBio-functionalOligomeric proantho cyanidinsTissue engineering

Identifiers

PMID39286229
PMCPMC11402651

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.