Evidence map›Paper›PMID 39287712›Full record

ReviewCurrent obesity reports2024

Mitochondrial Health Markers and Obesity-Related Health in Human Population Studies: A Narrative Review of Recent Literature.

Pei Wen Tung, Vidhu V Thaker, Dympna Gallagher, Allison Kupsco

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current obesity reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pei Wen TungDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA. pt2407@cumc.columbia.edu.
Vidhu V ThakerDepartment of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.
Dympna GallagherDepartment of Medicine, Columbia University Irving Medical Center , New York, NY, USA.
Allison KupscoDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.

Funding

RESEARCH TRAININGP30DK026687 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI Anthony W Ferrante, DYMPNA GALLAGHER · 1986 to 2026
$33.0M
NIDDK NIH HHS P30 DK026687
6 · The paper itself

Abstract

purpose of reviewThis narrative review summarizes current literature on the relationship of mitochondrial biomarkers with obesity-related characteristics, including body mass index and body composition. RECENT

findingsMitochondria, as cellular powerhouses, play a pivotal role in energy production and the regulation of metabolic process. Altered mitochondrial functions contribute to obesity, yet evidence of the intricate relationship between mitochondrial dynamics and obesity-related outcomes in human population studies is scarce and warrants further attention. We discuss emerging evidence linking obesity and related health outcomes to impaired oxidative phosphorylation pathways, oxidative stress and mtDNA variants, copy number and methylation, all hallmark of suboptimal mitochondrial function. We also explore the influence of dietary interventions and metabolic and bariatric surgery procedures on restoring mitochondrial attributes of individuals with obesity. Finally, we report on the potential knowledge gaps in the mitochondrial dynamics for human health for future study.

Indexed as

BiomarkersDNA, MitochondrialMitochondriaObesityBariatric SurgeryBody CompositionBody Mass IndexHumansMitochondrial DynamicsOxidative PhosphorylationOxidative StressBiomarkersDNA, MitochondrialAdiposityBariatric SurgeryEpidemiologyMitochondrial BiomarkersMitochondrial DNAObesity

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.