Evidence map›Paper›PMID 39287834›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

Effect of prehabilitation programmes on functional capacity in patients awaiting oncological resections: a systematic review and meta-analysis of randomised controlled trials.

Roberto Laza-Cagigas, Eneko Larumbe-Zabala, Tara Rampal, Marcos Seijo, Fernando Naclerio

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A trifold prehabilitation model prior to induction chemotherapy in patients with leukemia: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Trial
  3. Review
  4. Prehabilitation and postoperative outcomes in colorectal surgery: an umbrella review.Journal of anesthesia, analgesia and critical care · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. [App-based prehabilitation: implementation and adherence].Chirurgie (Heidelberg, Germany) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Roberto Laza-CagigasInstitute for Lifecourse Development, Centre for Exercise Activity and Rehabilitation, School of Human Science, University of Greenwich, Sparrows Farm (Office SF112B), Sparrows Lane, Avery Hill Campus, Eltham, SE9 2TB, England, UK.ORCID http://orcid.org/0000-0002-6735-2778
Eneko Larumbe-ZabalaDepartment of Public Health, Fundación Canaria Instituto de Investigación Sanitaria de Canarias, Las Palmas de Gran Canaria, Spain.ORCID http://orcid.org/0000-0002-8949-0602
Tara RampalQuestPrehab, London, UK.ORCID http://orcid.org/0000-0003-4262-0526
Marcos SeijoInstitute for Lifecourse Development, Centre for Exercise Activity and Rehabilitation, School of Human Science, University of Greenwich, Sparrows Farm (Office SF112B), Sparrows Lane, Avery Hill Campus, Eltham, SE9 2TB, England, UK.ORCID http://orcid.org/0000-0003-1637-6670
Fernando NaclerioInstitute for Lifecourse Development, Centre for Exercise Activity and Rehabilitation, School of Human Science, University of Greenwich, Sparrows Farm (Office SF112B), Sparrows Lane, Avery Hill Campus, Eltham, SE9 2TB, England, UK. f.j.naclerio@greenwich.ac.uk.ORCID http://orcid.org/0000-0001-7405-4894

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the effects of prehabilitation on the perioperative functional capacity of patients awaiting oncological resections.

methodsA systematic review and meta-analysis were performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) checklist and within the databases Cochrane Library, EBSCOhost, Google Scholar, MEDLINE PubMed, and Web of Science. The eligibility criteria were set to include peer-reviewed randomised control trials including only adult (≥ 18 years old) patients undergoing any type of prehabilitation (PREHAB) prior to any type of oncological resection. The studies had to feature at least one control group undergoing standard care (SC) and had to assess functional capacity by means of a 6-min walk distance (6MWD) or peak oxygen uptake (VO

resultsTwenty-seven randomised controlled trials involving 1994 patients were included. After processing the data, the number of patients was 1889. Studies featured different cancer specialties: lung (11), colorectal (5), urological (4), abdominal (3), esophagogastric (2), liver (1), and gastrointestinal (1). Overall, PREHAB enhanced both 6MWD (g = 0.273, 95% CI 0.174 to 0.371, Z = 5.406, p < 0.001) and VO

conclusionThese findings support that prehabilitation, whether implemented as unimodal or multimodal format, elicits small preoperative improvements in functional capacity in patients awaiting oncological resections. PROSPERO registration number CRD42023428676.

Indexed as

NeoplasmsPreoperative ExerciseHumansOxygen ConsumptionRandomized Controlled Trials as TopicCancerExerciseSurgery

Identifiers

PMID39287834
PMCPMC11408567

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.