Salivary and Serum Analytes and Their Associations with Self-rated Health Among Healthy Young Adults.

Angelina Majeno, Douglas A Granger, Crystal I Bryce, Jenna L Riis

Abstract read

In one paragraph

Article in International journal of behavioral medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Self-rated health and inflammation: Associations among partnered sexual minority and heterosexual adults.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Angelina MajenoDepartment of Psychological Science, 4201 Social and Behavioral Sciences Gateway, University of California Irvine, Irvine, CA, 92697-7085, USA. Angelina.Majeno@uci.edu.ORCID http://orcid.org/0000-0001-9031-9354

Douglas A GrangerInstitute for Interdisciplinary Salivary Bioscience Research, University of California Irvine, Irvine, CA, USA.ORCID http://orcid.org/0000-0002-1355-0218

Crystal I BryceSchool of Medicine, The University of Texas at Tyler, Tyler, TX, USA.ORCID http://orcid.org/0000-0002-1995-9356

Jenna L RiisInstitute for Interdisciplinary Salivary Bioscience Research, University of California Irvine, Irvine, CA, USA.ORCID http://orcid.org/0000-0001-8563-3074

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnderstanding the biological processes underlying poor self-rated health (SRH) can inform prevention efforts. The COVID-19 pandemic highlighted the importance of using self-reported measures and self-collected biospecimens, such as saliva, to understand physiological functioning and assist with health surveillance and promotion. However, the associations between salivary analytes and SRH remain understudied. The current study addresses this gap.

methodsIn a laboratory-based study, 99 healthy adults (M

resultsSalivary analytes loaded onto two components (component 1: adiponectin and cytokines; component 2: CRP and UA) explaining 58% of the variance. Serum analytes grouped onto three components (component 1: IL-8 and TNF-α; component 2: CRP, IL-1β, and IL-6; component 3: adiponectin and UA) explaining 76% of the variance. Higher salivary component 1 scores predicted higher odds of reporting poor SRH (OR 1.53, 95%CI [1.10, 2.11]). Higher serum component 2 scores predicted higher odds of reporting poor SRH (OR 2.37, 95%CI [1.20, 4.67]). When examined in the same model, salivary component 1 (OR 1.79, 95%CI [1.17, 2.75]) and serum component 2 were associated with poorer SRH (OR 7.74, 95%CI [2.18, 27.40]).

conclusionsIn our sample, whether measured in saliva or serum, indices of inflammatory processes were associated with SRH.

Indexed as

CytokinesHealth StatusSalivaAdiponectinAdultBiomarkersCOVID-19C-Reactive ProteinFemaleHumansMaleSelf ReportUric AcidYoung AdultAdiponectinBiomarkersC-Reactive ProteinCytokinesUric AcidC-Reactive proteinCytokineInflammationSalivaSelf-rated healthSerumSubjective health

Identifiers

PMID39289251

DOI10.1016/j.psyneuen.2009.12.009

What Socratic holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.